Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.31 |
| ▸ | CCRL2 | O00421 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8269012 | 1.00 | FFAR1 (0.31) | FFAR1CCRL2 | |
| SCHEMBL8269240 | 0.91 | FFAR4 (0.35) | FFAR1 | |
| SCHEMBL8269244 | 0.91 | FFAR4 (0.35) | FFAR1 | |
| SCHEMBL13611630 | 0.91 | FFAR4 (0.35) | FFAR1 | |
| SCHEMBL13611866 | 0.87 | — | — | |
| SCHEMBL13611867 | 0.87 | — | — | |
| SCHEMBL13513844 | 0.85 | FFAR4 (0.37) | FFAR1 | |
| SCHEMBL8268251 | 0.83 | — | — | |
| SCHEMBL13513845 | 0.80 | ALDH1A1 (0.34) | FFAR1CCRL2 | |
| SCHEMBL13604442 | 0.80 | ALDH1A1 (0.34) | FFAR1CCRL2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805141-B1 | PIPERIDINES AND RELATED COMPOUNDS FOR TREATMENT OF ALZHEIMER'S DISEASE | MERCK SHARP & DOHME (GB) | 2010-01-20 | — | — | EP | disclosed |
| WO-2006043064-A1 | PIPERIDINES AND RELATED COMPOUNDS FOR TREATMENT OF ALZHEIMER'S DISEASE | MERCK SHARP & DOHME LIMITED (GB) | 2006-04-27 | — | — | WO | disclosed |