⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13611867 | 0.87 | — | — | |
| SCHEMBL13611866 | 0.87 | — | — | |
| SCHEMBL13611630 | 0.86 | FFAR4 (0.35) | — | |
| SCHEMBL8269240 | 0.86 | FFAR4 (0.35) | — | |
| SCHEMBL8269244 | 0.86 | FFAR4 (0.35) | — | |
| SCHEMBL8269013 | 0.83 | FFAR1 (0.31) | — | |
| SCHEMBL8269012 | 0.83 | FFAR1 (0.31) | — | |
| SCHEMBL8268224 | 0.81 | FFAR1 (0.33) | — | |
| SCHEMBL13513844 | 0.77 | FFAR4 (0.37) | — | |
| SCHEMBL8268942 | 0.74 | FFAR1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006043064-A1 | PIPERIDINES AND RELATED COMPOUNDS FOR TREATMENT OF ALZHEIMER'S DISEASE | MERCK SHARP & DOHME LIMITED (GB) | 2006-04-27 | — | — | WO | disclosed |