SCHEMBL13611895

SCHEMBL13611895

CC(C)(C)NC(=O)C(C)(C)NC(=O)C(C)(C)C

nearest known ligand 0.36

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.36
EPHX1 P07099 1/20 0.34
CYP1A2 P05177 1/20 0.34
PKM P14618 1/20 0.34
PTK2B Q14289 1/20 0.34
POLB P06746 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL153717 0.89 L3MBTL1 (0.42) L3MBTL1EPHX1CYP1A2PKMPTK2B
SCHEMBL13542985 0.78 L3MBTL1 (0.39) L3MBTL1CYP1A2PKMPTK2B
SCHEMBL14040406 0.76 KDM4C (0.45) L3MBTL1CYP1A2PKMPTK2BPOLB
SCHEMBL19964618 0.76 EPHX1 (0.36) EPHX1POLBMEN1KMT2A
SCHEMBL6276759 0.76 EPHX1 (0.36) EPHX1POLBMEN1KMT2A
SCHEMBL21137601 0.75 KMT2A (0.36) KMT2A
SCHEMBL15079429 0.74 L3MBTL1 (0.36) L3MBTL1CYP1A2PKMPTK2B
SCHEMBL18902033 0.74 EPHX1 (0.34) EPHX1POLBMEN1KMT2A
SCHEMBL23095629 0.72 L3MBTL1 (0.34) L3MBTL1CYP1A2PKMPTK2B
SCHEMBL17399505 0.72 DGAT1 (0.39) L3MBTL1CYP1A2PKMPTK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090291998-A1 EPONEMYCIN AND EPOXOMICIN ANALOGS AND USES THEREOF EISAI R&D MANAGEMENT CO., LTD. 2009-11-26 US disclosed
US-7524883-B2 Eponemycin and epoxomicin analogs and uses thereof EISAI R&D MANAGEMENT CO., LTD. (JP) 2009-04-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090291998-A1 EPONEMYCIN AND EPOXOMICIN ANALOGS AND USES THEREOF PSMC4, PSMB6, EPOR L3MBTL1 2058/4885EPHX1 463/4885CYP1A2 2084/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.