Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13626168 | 1.00 | POLB (0.39) | POLBNPSR1TRPA1 | |
| SCHEMBL13611899 | 0.88 | POLB (0.39) | POLBNPSR1TRPA1 | |
| SCHEMBL24435902 | 0.82 | POLB (0.41) | POLBTRPA1 | |
| SCHEMBL17432119 | 0.79 | GAA (0.33) | POLBNPSR1 | |
| SCHEMBL17373361 | 0.79 | CA2 (0.39) | POLBNPSR1 | |
| SCHEMBL17407698 | 0.79 | POLB (0.42) | POLBNPSR1 | |
| SCHEMBL684795 | 0.79 | L3MBTL1 (0.35) | POLBNPSR1 | |
| SCHEMBL684475 | 0.79 | L3MBTL1 (0.35) | POLBNPSR1 | |
| SCHEMBL17373358 | 0.79 | CA2 (0.39) | POLBNPSR1 | |
| SCHEMBL28433567 | 0.79 | CA2 (0.39) | POLBNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291998-A1 | EPONEMYCIN AND EPOXOMICIN ANALOGS AND USES THEREOF | EISAI R&D MANAGEMENT CO., LTD. | 2009-11-26 | — | — | US | disclosed |
| US-7524883-B2 | Eponemycin and epoxomicin analogs and uses thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291998-A1 | EPONEMYCIN AND EPOXOMICIN ANALOGS AND USES THEREOF | PSMC4, PSMB6, EPOR | POLB 2096/4885NPSR1 1908/4885TRPA1 4846/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.