Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACMSD | Q8TDX5 | 5/20 | 0.60 |
| ▸ | MCL1 | Q07820 | 5/20 | 0.60 |
| ▸ | HNF4A | P41235 | 2/20 | 0.60 |
| ▸ | DHFR | P00374 | 1/20 | 0.60 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.55 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.49 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.46 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.46 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.46 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.46 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13611936 | 0.84 | MAPT (0.46) | ACMSDMCL1HNF4ADHFRGSTA1 | |
| SCHEMBL28710614 | 0.82 | ACMSD (0.66) | ACMSDMCL1HNF4ADHFRGSTA1 | |
| SCHEMBL2605694 | 0.80 | ALOX5AP (0.49) | ACMSDHNF4ANPC1LMNAMAPT | |
| SCHEMBL6280743 | 0.79 | MCL1 (0.66) | ACMSDMCL1HNF4ADHFRGSTA1 | |
| SCHEMBL13626334 | 0.78 | ACMSD (0.60) | ACMSDMCL1HNF4ADHFRGSTA1 | |
| SCHEMBL7757842 | 0.78 | KDM4E (0.59) | KDM4ENPC1LMNAMAPT | |
| SCHEMBL6282455 | 0.78 | TMPRSS4 (0.67) | ACMSDMCL1HNF4ADHFRGSTA1 | |
| SCHEMBL2070297 | 0.76 | MCL1 (0.72) | ACMSDMCL1HNF4ADHFRGSTA1 | |
| Bromide SCHEMBL6849900 | 0.76 | KDM4E (0.57) | KDM4ENPC1LMNAMAPT | |
| SCHEMBL6416083 | 0.76 | NPC1 (0.60) | KDM4ENPC1LMNAMAPTCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090291998-A1 | EPONEMYCIN AND EPOXOMICIN ANALOGS AND USES THEREOF | EISAI R&D MANAGEMENT CO., LTD. | 2009-11-26 | — | — | US | disclosed |
| US-7524883-B2 | Eponemycin and epoxomicin analogs and uses thereof | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2009-04-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090291998-A1 | EPONEMYCIN AND EPOXOMICIN ANALOGS AND USES THEREOF | PSMC4, PSMB6, EPOR | ACMSD 3067/4885MCL1 356/4885HNF4A 4587/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.