Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 3/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.36 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.34 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.33 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.33 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.33 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.33 |
| ▸ | TNF | P01375 | 3/20 | 0.33 |
| ▸ | EIF4E | P06730 | 1/20 | 0.33 |
| ▸ | PDE9A | O76083 | 1/20 | 0.32 |
| ▸ | GPR6 | P46095 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | PRKDC | P78527 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13613336 | 0.93 | ALDH1A1 (0.38) | IRAK4EGLN2SLC22A12KDM4ENR3C1 | |
| SCHEMBL4493595 | 0.89 | EGLN2 (0.37) | EGLN2SLC22A12KDM4ENR3C1TNF | |
| SCHEMBL4513063 | 0.89 | EGLN2 (0.37) | EGLN2SLC22A12KDM4ENR3C1TNF | |
| SCHEMBL4503659 | 0.85 | SLC22A12 (0.36) | IRAK4EGLN2SLC22A12KDM4ENR3C1 | |
| SCHEMBL4493601 | 0.83 | TP53 (0.39) | IRAK4EGLN2SLC22A12KDM4EEIF4E | |
| SCHEMBL4506052 | 0.81 | MAPT (0.36) | IRAK4EGLN2SLC22A12KDM4ENR3C1 | |
| SCHEMBL4499615 | 0.81 | MAPT (0.36) | IRAK4EGLN2SLC22A12KDM4ENR3C1 | |
| SCHEMBL14463731 | 0.79 | CDK2 (0.42) | KDM4E | |
| SCHEMBL4514267 | 0.78 | DPP4 (0.38) | EGLN2SLC22A12KDM4EEIF4EDPP4 | |
| SCHEMBL3531293 | 0.78 | DPP4 (0.42) | KDM4EDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629294-B2 | Pyrazolopyrimidines | BAYER CROPSCIENCE LP (DE) | 2009-12-08 | — | — | US | disclosed |