Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | CASP1 | P29466 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CASP7 | P55210 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13613292 | 0.93 | IRAK4 (0.36) | KDM4EKMT2AMEN1NR3C1IRAK4 | |
| SCHEMBL4506052 | 0.89 | MAPT (0.36) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL4499615 | 0.89 | MAPT (0.36) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL4499619 | 0.84 | TP53 (0.38) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL4510189 | 0.83 | MAPT (0.41) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL4513063 | 0.81 | EGLN2 (0.37) | KDM4EHSD17B10TSHRGAASMN1; SMN2 | |
| SCHEMBL4493595 | 0.81 | EGLN2 (0.37) | KDM4EHSD17B10TSHRGAASMN1; SMN2 | |
| SCHEMBL4505734 | 0.80 | EGLN2 (0.40) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL3536230 | 0.79 | DPP4 (0.40) | ALDH1A1KDM4EHPGDHSD17B10CASP1 | |
| SCHEMBL4507978 | 0.78 | ALDH1A1 (0.37) | ALDH1A1KDM4EHPGDHSD17B10CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7629294-B2 | Pyrazolopyrimidines | BAYER CROPSCIENCE LP (DE) | 2009-12-08 | — | — | US | disclosed |