Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3193799 | 0.78 | ALDH1A1 (0.39) | KDRTDP1 | |
| SCHEMBL3214515 | 0.78 | KEAP1 (0.39) | TDP1 | |
| SCHEMBL3214507 | 0.75 | KDM4E (0.51) | — | |
| SCHEMBL3206362 | 0.75 | ALDH1A1 (0.46) | — | |
| SCHEMBL12651209 | 0.74 | CYP2C19 (0.36) | TDP1 | |
| SCHEMBL3203132 | 0.74 | TDP1 (0.48) | TDP1 | |
| SCHEMBL2926444 | 0.68 | PSEN1 (0.36) | — | |
| SCHEMBL18172056 | 0.68 | S1PR3 (0.43) | — | |
| SCHEMBL18172071 | 0.66 | PDE2A (0.49) | KDR | |
| SCHEMBL2924123 | 0.65 | EEF2K (0.38) | KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2119703-B1 | NOVEL INDOLE DERIVATIVE HAVING INHIBITORY ACTIVITY ON I B KINASE | SANTEN PHARMACEUTICAL CO LTD (JP) | 2012-12-12 | — | — | EP | disclosed |
| EP-2119703-A1 | NOVEL INDOLE DERIVATIVE HAVING INHIBITORY ACTIVITY ON I B KINASE | Santen Pharmaceutical Co., Ltd (JP) | 2009-11-18 | — | — | EP | disclosed |