Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13613594 | 1.00 | NR1H2 (0.43) | NR1H2ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL13613597 | 1.00 | NR1H2 (0.43) | NR1H2ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL2911226 | 0.86 | RIPK1 (0.38) | LMNATSHRNPC1RIPK1 | |
| SCHEMBL2910772 | 0.86 | MEN1 (0.43) | NR1H2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL2910770 | 0.86 | MEN1 (0.43) | NR1H2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL2914617 | 0.86 | MEN1 (0.43) | NR1H2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL25594973 | 0.81 | LMNA (0.48) | NR1H2ALDH1A1LMNANPSR1MAPT | |
| SCHEMBL13628052 | 0.80 | NR1H2 (0.45) | NR1H2ALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL2695856 | 0.80 | NR1H2 (0.46) | NR1H2ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL1922847 | 0.80 | NR1H2 (0.46) | NR1H2ALDH1A1MEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7622585-B2 | Phenylglycinamide derivatives useful as anticoagulants | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-11-24 | — | — | US | disclosed |