Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 3/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | GLS | O94925 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13613731 | 1.00 | TOP2A (0.34) | TOP2ANR1H2FKBP1AFAAHCHRM2 | |
| SCHEMBL26045071 | 1.00 | TOP2A (0.34) | TOP2ANR1H2FKBP1AFAAHCHRM2 | |
| SCHEMBL29580091 | 0.85 | FKBP1A (0.31) | TOP2ANR1H2FKBP1AFAAHCHRM2 | |
| SCHEMBL29580011 | 0.85 | FKBP1A (0.31) | TOP2ANR1H2FKBP1AFAAHCHRM2 | |
| SCHEMBL30337705 | 0.82 | GAA (0.40) | ALDH1A1 | |
| SCHEMBL7067181 | 0.81 | SMYD2 (0.39) | — | |
| SCHEMBL30683282 | 0.81 | SMYD2 (0.39) | — | |
| SCHEMBL7518554 | 0.81 | SMYD2 (0.39) | — | |
| SCHEMBL7063383 | 0.80 | NR1H2 (0.43) | NR1H2CHRM2CHRM1CHRM3 | |
| SCHEMBL12531098 | 0.80 | NR1H2 (0.43) | NR1H2CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275727-A1 | Peptide turn mimetics | MIMETICA PTY LIMITED (AU) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275727-A1 | Peptide turn mimetics | IAPP, GLP1R, VIP | TOP2A 3520/4885NR1H2 2948/4885FKBP1A 2350/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.