Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | STS | P08842 | 4/20 | 0.37 |
| ▸ | P2RY12 | Q9H244 | 4/20 | 0.37 |
| ▸ | HRH1 | P35367 | 4/20 | 0.35 |
| ▸ | CCR3 | P51677 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | KIT | P10721 | 1/20 | 0.33 |
| ▸ | HRH2 | P25021 | 1/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13613823 | 0.94 | LMNA (0.41) | STSP2RY12HRH1CCR3LMNA | |
| SCHEMBL13613812 | 0.86 | FAAH (0.42) | IDO1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL13613810 | 0.86 | TLR7 (0.39) | MEN1KMT2ALMNAPOLBTLR7 | |
| SCHEMBL13613815 | 0.84 | LCK (0.36) | KDM4EMAPTHTTLMNAPOLB | |
| SCHEMBL13613811 | 0.84 | TLR7 (0.39) | MEN1KMT2ALMNAPOLBTLR7 | |
| SCHEMBL13999873 | 0.83 | NPY5R (0.39) | KDM4EMEN1HTTKMT2ALMNA | |
| SCHEMBL13613819 | 0.82 | EPHX2 (0.41) | KCNH2 | |
| SCHEMBL4338051 | 0.82 | TLR7 (0.40) | KDM4ELMNAPOLBTLR7KCNH2 | |
| SCHEMBL13613813 | 0.82 | TLR7 (0.38) | KDM4ELMNAPOLBTLR7KCNH2 | |
| SCHEMBL13999889 | 0.82 | NPY5R (0.37) | MEN1HTTKMT2ALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612083-B2 | Urea substituted imidazoquinoline ethers | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2009-11-03 | — | — | US | disclosed |
| US-7612083-B2 | Urea substituted imidazoquinoline ethers | COLEY PHARMACEUTICAL GROUP, INC. (US) | 2009-11-03 | — | — | US | disclosed |
| US-7214675-B2 | Urea substituted imidazoquinoline ethers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-05-08 | — | — | US | disclosed |
| US-7214675-B2 | Urea substituted imidazoquinoline ethers | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-05-08 | — | — | US | disclosed |