Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 2/20 | 0.44 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8520097 | 0.95 | NAAA (0.41) | NAAASLC18A3ALDH1A1LMNAPOLB | |
| SCHEMBL3346305 | 0.90 | NAAA (0.53) | NAAAMEN1KMT2ALMNAPOLB | |
| SCHEMBL27564579 | 0.89 | ALDH1A1 (0.43) | NAAASLC18A3ALDH1A1 | |
| SCHEMBL6901495 | 0.89 | NAAA (0.59) | NAAA | |
| SCHEMBL7172961 | 0.87 | NAAA (0.62) | NAAA | |
| SCHEMBL10342906 | 0.87 | NAAA (0.62) | NAAA | |
| SCHEMBL28466767 | 0.87 | NAAA (0.62) | NAAA | |
| SCHEMBL20357987 | 0.86 | CHRM2 (0.38) | NAAAALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL3812571 | 0.86 | CHRM2 (0.38) | NAAAALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL26696399 | 0.85 | NAAA (0.50) | NAAALMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020118178-A1 | MONOMETHYL FUMARATE-CARRIER CONJUGATES AND METHODS OF THEIR USE | FLAGSHIP PIONEERING INNOVATIONS V, INC. (US) | 2020-06-11 | — | — | WO | disclosed |
| WO-2016095088-A1 | ERK INHIBITORS | MERCK SHARP & DOHME CORP. (US) | 2016-06-23 | — | — | WO | disclosed |
| EP-1538173-B1 | Hydrogenated ring-opening metathesis polymer and process for producing the same | MITSUI CHEMICALS INC (JP) | 2009-11-04 | — | — | EP | disclosed |
| US-7435527-B2 | Mixture of acid generator and resin insoluble in alkaline developer and another acid decomposable compound | FUJIFILM CORPORATION (JP) | 2008-10-14 | — | — | US | disclosed |