Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13614232 | 0.76 | CA12 (0.56) | L3MBTL1CA12CA9LMNAALDH1A1 | |
| SCHEMBL691736 | 0.70 | GRIA1 (0.48) | LMNAALDH1A1MAPTCYP3A4CYP2C19 | |
| SCHEMBL3528445 | 0.70 | CA12 (0.58) | L3MBTL1CA12CA9POLBALDH1A1 | |
| SCHEMBL13684737 | 0.69 | CA12 (0.47) | L3MBTL1CA12CA9POLBLMNA | |
| SCHEMBL13542944 | 0.68 | CA12 (0.49) | L3MBTL1CA12CA9POLBCA1 | |
| SCHEMBL3555918 | 0.67 | CA12 (0.59) | L3MBTL1CA12CA9POLBCA1 | |
| SCHEMBL3528864 | 0.67 | CA12 (0.55) | L3MBTL1CA12CA9POLBCA1 | |
| SCHEMBL801417 | 0.66 | TDP1 (0.62) | L3MBTL1POLBLMNAHTTALDH1A1 | |
| SCHEMBL9700422 | 0.66 | GRIA1 (0.41) | L3MBTL1ALDH1A1MAPTCYP3A4CYP2C19 | |
| SCHEMBL32664495 | 0.65 | CA12 (0.61) | L3MBTL1CA12CA9POLBCA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1432700-B1 | SPIRO-HYDANTOIN COMPOUNDS USEFUL AS ANTI-INFLAMMATORY AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2009-11-04 | — | — | EP | disclosed |