Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 8/20 | 0.40 |
| ▸ | CES1 | P23141 | 5/20 | 0.40 |
| ▸ | CES2 | O00748 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8763791 | 1.00 | PAOX (0.50) | PAOXALDH1A1FAAHCES1CES2 | |
| SCHEMBL379594 | 1.00 | PAOX (0.50) | PAOXALDH1A1FAAHCES1CES2 | |
| SCHEMBL13656097 | 1.00 | PAOX (0.50) | PAOXALDH1A1FAAHCES1CES2 | |
| SCHEMBL13656100 | 1.00 | PAOX (0.50) | PAOXALDH1A1FAAHCES1CES2 | |
| SCHEMBL5172758 | 1.00 | PAOX (0.50) | PAOXALDH1A1FAAHCES1CES2 | |
| SCHEMBL9969983 | 0.98 | PAOX (0.46) | PAOXALDH1A1FAAHCES1CES2 | |
| SCHEMBL9935032 | 0.90 | ALDH1A1 (0.45) | PAOXALDH1A1FAAHCES1CES2 | |
| SCHEMBL816436 | 0.80 | PAOX (0.41) | PAOXALDH1A1FAAHCES1CES2 | |
| SCHEMBL6647762 | 0.79 | — | — | |
| SCHEMBL26971258 | 0.79 | PAOX (0.43) | PAOXALDH1A1FAAHCES1CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3922728-B1 | METHOD FOR PRODUCING (1R,3R)-3-(TRIFLUOROMETHYL)CYCLOHEXAN-1-OL AND INTERMEDIATE THEREOF | API CORP (JP) | 2023-11-29 | — | — | EP | disclosed |
| US-7612238-B2 | Such as (R)-2-amino-2-methyl-4-[4-(4,4,5,5,5-pentafluoro-pentyloxy)-phenyl]-butan-1-ol hydrochloride for treatment of disorders or diseases mediated by lymphocytes, and for treating acute or chronic transplant rejection or T-cell-mediated inflammatory or autoimmune diseases | NOVARTIS AG (CH) | 2009-11-03 | — | — | US | disclosed |
| US-7612238-B2 | Such as (R)-2-amino-2-methyl-4-[4-(4,4,5,5,5-pentafluoro-pentyloxy)-phenyl]-butan-1-ol hydrochloride for treatment of disorders or diseases mediated by lymphocytes, and for treating acute or chronic transplant rejection or T-cell-mediated inflammatory or autoimmune diseases | NOVARTIS AG (CH) | 2009-11-03 | — | — | US | disclosed |