Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 4/20 | 0.41 |
| ▸ | FAAH | O00519 | 7/20 | 0.37 |
| ▸ | CES1 | P23141 | 5/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL148224 | 0.84 | PAOX (0.54) | PAOXCES2MEN1KMT2AGAA | |
| SCHEMBL815907 | 0.83 | ALDH1A1 (0.48) | MEN1KMT2AHSD17B10HDAC1HDAC2 | |
| SCHEMBL30497656 | 0.83 | ALDH1A1 (0.48) | MEN1KMT2AHSD17B10HDAC1HDAC2 | |
| SCHEMBL814585 | 0.82 | TSHR (0.47) | CES2MEN1KMT2APLA2G2CGAA | |
| SCHEMBL814157 | 0.81 | ALDH1A1 (0.41) | CES2FAAHCES1MEN1CYP1A2 | |
| SCHEMBL19043440 | 0.81 | PLA2G2C (0.45) | PAOXCES2FAAHCES1MEN1 | |
| SCHEMBL13656097 | 0.80 | PAOX (0.50) | PAOXCES2FAAHCES1MEN1 | |
| SCHEMBL5172758 | 0.80 | PAOX (0.50) | PAOXCES2FAAHCES1MEN1 | |
| SCHEMBL379594 | 0.80 | PAOX (0.50) | PAOXCES2FAAHCES1MEN1 | |
| SCHEMBL13656100 | 0.80 | PAOX (0.50) | PAOXCES2FAAHCES1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8067625-B2 | Fluorosurfactants | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-11-29 | — | — | US | disclosed |
| US-20090264525-A1 | FLUOROSURFACTANTS | MERCK PATENT GMBH (DE) | 2009-10-22 | — | — | US | disclosed |
| WO-2008003444-A1 | FLUOROSURFACANTS | MERCK PATENT GMBH (DE) | 2008-01-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264525-A1 | FLUOROSURFACTANTS | FASN, FFAR3, SGMS2 | PAOX 93/4885CES2 385/4885FAAH 151/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.