Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.32 |
| ▸ | AIMP2 | Q13155 | 2/20 | 0.32 |
| ▸ | F2 | P00734 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4344712 | 0.89 | TDP1 (0.39) | NPY5RAIMP2MEN1KMT2ABDKRB1 | |
| SCHEMBL4344707 | 0.89 | TDP1 (0.39) | NPY5RAIMP2MEN1KMT2ABDKRB1 | |
| SCHEMBL5002032 | 0.88 | AIMP2 (0.35) | AIMP2F2MEN1KMT2ABDKRB1 | |
| SCHEMBL5002026 | 0.88 | AIMP2 (0.35) | AIMP2F2MEN1KMT2ABDKRB1 | |
| SCHEMBL5107016 | 0.80 | TDP1 (0.42) | AIMP2MEN1KMT2AITGB3ITGA2B | |
| SCHEMBL5001780 | 0.76 | BDKRB1 (0.45) | NPY5RBDKRB1ITGB3ITGA2BMMP9 | |
| SCHEMBL5001778 | 0.76 | BDKRB1 (0.45) | NPY5RBDKRB1ITGB3ITGA2BMMP9 | |
| SCHEMBL5001845 | 0.76 | BDKRB1 (0.41) | AIMP2MEN1KMT2ABDKRB1SMN1; SMN2 | |
| SCHEMBL5001844 | 0.76 | BDKRB1 (0.41) | AIMP2MEN1KMT2ABDKRB1SMN1; SMN2 | |
| SCHEMBL4331450 | 0.75 | MMP9 (0.41) | F2ITGB3ITGA2BMMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7612060-B2 | Triazoles and methods of use | AMGEN INC. (US) | 2009-11-03 | — | — | US | disclosed |