Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 11/20 | 0.53 |
| ▸ | CA9 | Q16790 | 11/20 | 0.53 |
| ▸ | CA1 | P00915 | 10/20 | 0.53 |
| ▸ | CA6 | P23280 | 5/20 | 0.53 |
| ▸ | CA7 | P43166 | 5/20 | 0.53 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.53 |
| ▸ | CA4 | P22748 | 5/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | CA5A | P35218 | 3/20 | 0.53 |
| ▸ | CA3 | P07451 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | GLA | P06280 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12337641 | 1.00 | MAOA (0.56) | MAOACA12CA9CA1CA6 | |
| SCHEMBL14515315 | 0.84 | MAOA (0.54) | MAOACA12CA9CA1CA6 | |
| SCHEMBL14515224 | 0.84 | MAOA (0.54) | MAOACA12CA9CA1CA6 | |
| SCHEMBL14515212 | 0.84 | MAOA (0.54) | MAOACA12CA9CA1CA6 | |
| SCHEMBL14515312 | 0.84 | MAOA (0.54) | MAOACA12CA9CA1CA6 | |
| SCHEMBL14539461 | 0.84 | MAOA (0.54) | MAOACA12CA9CA1CA6 | |
| SCHEMBL14515223 | 0.84 | MAOA (0.54) | MAOACA12CA9CA1CA6 | |
| SCHEMBL16674816 | 0.84 | MAOA (0.68) | MAOACA12CA9CA1CA6 | |
| Ip-2018 SCHEMBL25368803 | 0.83 | SLC6A4 (0.59) | MAOACA12CA9CA1CA6 | |
| Ip-2018 SCHEMBL1103728 | 0.83 | SLC6A4 (0.59) | MAOACA12CA9CA1CA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090312364-A1 | NOVEL CHROMEN-2-ONE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2009-12-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090312364-A1 | NOVEL CHROMEN-2-ONE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | SLC6A2, SLC18A2, SLC18A1 | MAOA 7/4885CA12 3506/4885CA9 4370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.