Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.40 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10018705 | 1.00 | ACHE (0.43) | ACHEPTGS2TDP1PTGS1RPS6KA3 | |
| SCHEMBL14365638 | 0.93 | ACHE (0.39) | ACHEPTGS2TDP1PTGS1RPS6KA3 | |
| SCHEMBL25573565 | 0.88 | GRM5 (0.41) | ACHEPTGS2PTGS1RPS6KA3CYP11B1 | |
| SCHEMBL12977254 | 0.88 | TEAD4 (0.45) | ACHETDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL10014228 | 0.85 | ACHE (0.43) | ACHEPTGS2TDP1PTGS1RPS6KA3 | |
| SCHEMBL8192072 | 0.85 | ACHE (0.43) | ACHEPTGS2TDP1PTGS1RPS6KA3 | |
| SCHEMBL16258106 | 0.85 | ACHE (0.43) | ACHEPTGS2TDP1PTGS1RPS6KA3 | |
| SCHEMBL10024800 | 0.85 | PDE3B (0.42) | ACHEPTGS2PTGS1RPS6KA3MEN1 | |
| SCHEMBL4438303 | 0.85 | PDE3B (0.42) | ACHEPTGS2PTGS1RPS6KA3MEN1 | |
| SCHEMBL18673225 | 0.84 | HDAC1 (0.42) | ACHETDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180155625-A1 | LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME | MERCK PATENT GMBH (DE) | 2018-06-07 | — | — | US | disclosed |
| US-20180105748-A1 | LIQUID-CRYSTALLINE MEDIUM, COMPOUNDS, AND HIGH-FREQUENCY COMPONENTS | MERCK PATENT GMBH (DE) | 2018-04-19 | — | — | US | disclosed |
| US-20170349832-A1 | LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME | MERCK PATENT GMBH (DE) | 2017-12-07 | — | — | US | disclosed |
| WO-2017194665-A1 | BIMESOGENIC COMPOUNDS AND MESOGENIC MEDIA | MERCK PATENT GMBH (DE) | 2017-11-16 | — | — | WO | disclosed |
| US-20170130129-A1 | LIQUID-CRYSTALLINE MEDIUM AND HIGH-FREQUENCY COMPONENTS COMPRISING SAME | MERCK PATENT GMBH (DE) | 2017-05-11 | — | — | US | disclosed |
| US-9593279-B2 | Liquid-crystalline medium and high-frequency components comprising same | MERCK PATENT GMBH (DE) | 2017-03-14 | — | — | US | disclosed |
| US-20170029698-A1 | ANTIOXIDANT FOR LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE USING LIQUID CRYSTAL COMPOSITION | DIC CORPORATION (JP) | 2017-02-02 | — | — | US | disclosed |
| US-9487704-B2 | Nematic liquid crystal composition and liquid crystal display element using same | DIC CORPORATION (JP) | 2016-11-08 | — | — | US | disclosed |
| US-20160319195-A1 | NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING THE SAME | DIC CORPORATION (JP) | 2016-11-03 | — | — | US | disclosed |
| US-20160060526-A1 | NEMATIC LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT USING SAME | DIC CORPORATION (JP) | 2016-03-03 | — | — | US | disclosed |
| EP-2116522-A1 | PENTACYCLIC LIQUID CRYSTAL COMPOUND HAVING CF<SB>2</SB>O BONDING GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY | Chisso Corporation (JP) | 2009-11-11 | — | — | EP | disclosed |
| US-7462297-B2 | Chiral dopants having a laterally alkylated phenyl structural element | MERCK PATENT GMBH (DE) | 2008-12-09 | — | — | US | disclosed |
| US-7294368-B2 | Liquid crystal composition for use in bistable liquid crystal devices | MERCK PATENT GMBH (DE) | 2007-11-13 | — | — | US | disclosed |
| US-7258903-B2 | Fast switching liquid crystal compositions for use in bistable liquid crystal devices | MERCK PATENT GMBH (DE) | 2007-08-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170029698-A1 | ANTIOXIDANT FOR LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE USING LIQUID CRYSTAL COMPOSITION | GPX1, LPO, SCO2 | ACHE 2687/4885PTGS2 1216/4885TDP1 1138/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.