SCHEMBL20209568

SCHEMBL20209568

Fc1cc(C2OCCCO2)ccc1-c1cc(F)c(OCc2cc(F)c(F)c(F)c2)c(F)c1

nearest known ligand 0.33

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 3/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
MAOB P27338 1/20 0.31
ALOX5AP P20292 1/20 0.31
FEN1 P39748 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20209766 0.87 CYP11B1 (0.37) FFAR4CYP11B1CYP11B2MAOB
SCHEMBL19097982 0.87 MAOB (0.32) FFAR4MAOB
SCHEMBL19098118 0.86 PRKAG1 (0.38) FFAR4ALOX5APFEN1
SCHEMBL13614630 0.85 CYP11B1 (0.41) CYP11B1CYP11B2
SCHEMBL19082858 0.85 MAOB (0.31) FFAR4MAOB
SCHEMBL17806152 0.83 FFAR4 (0.31) FFAR4MAOB
SCHEMBL17799300 0.83 FFAR4 (0.31) FFAR4MAOB
SCHEMBL17799297 0.83 FFAR4 (0.31) FFAR4MAOB
SCHEMBL19261442 0.83 CYP11B1 (0.42) CYP11B1CYP11B2ALOX5APFEN1
SCHEMBL19082855 0.81 FFAR4 (0.30) FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200071617-A1 LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2020-03-05 US disclosed
US-20190119575-A1 LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY ELEMENT DIC CORPORATION (JP) 2019-04-25 US disclosed
US-20180148647-A1 COMPOSITION AND LIQUID CRYSTAL DISPLAY USING SAME DIC CORPORATION (JP) 2018-05-31 US disclosed