SCHEMBL17033199

SCHEMBL17033199

Fc1cc(C2OCCCO2)ccc1-c1cc(F)c(C(F)(F)Oc2cc(F)c(F)c(F)c2)c(F)c1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CYP11B1 P15538 2/20 0.33
CYP11B2 P19099 2/20 0.33
CETP P11597 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17033202 0.93 GRM2 (0.33) CYP11B1CYP11B2CETP
SCHEMBL15497674 0.88 GRM2 (0.32)
SCHEMBL21019383 0.87 CYP11B1 (0.37) CYP11B1CYP11B2
SCHEMBL16549409 0.87
SCHEMBL16546485 0.87
SCHEMBL17831343 0.87
SCHEMBL19478660 0.87 CYP11B1 (0.31) CYP11B1CYP11B2
SCHEMBL19557543 0.86 PRKAG1 (0.37)
SCHEMBL22846019 0.85 CYP11B1 (0.31) CYP11B1CYP11B2
SCHEMBL18820206 0.85 CYP11B1 (0.32) CYP11B1CYP11B2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12043782-B2 Liquid crystalline medium MERCK PATENT GMBH (DE) 2024-07-23 US disclosed
US-11718791-B2 Polymerisable compounds and the use thereof in liquid-crystal displays MERCK PATENT GMBH (DE) 2023-08-08 US disclosed
US-11702597-B2 Azo dye MERCK PATENT GMBH (DE) 2023-07-18 US disclosed
US-11685863-B2 Polymerisable compounds and the use thereof in liquid-crystal displays MERCK PATENT GMBH (DE) 2023-06-27 US disclosed
US-20230068853-A1 LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2023-03-02 US disclosed
US-20230007940-A1 LIQUID-CRYSTAL MEDIUM COMPRISING POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCKP PATENT GMBH (DE) 2023-01-12 US disclosed
US-11359141-B2 Additives for liquid crystal mixtures MERCK PATENT GMBH (DE) 2022-06-14 US disclosed
US-20220127532-A1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS MERCK PATENT GMBH (DE) 2022-04-28 US disclosed
US-11312909-B2 Polymerizable compounds and the use thereof in liquid-crystal displays MERCK PATENT GMBH (DE) 2022-04-26 US disclosed
US-20220119711-A1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2022-04-21 US disclosed
US-10738243-B2 Liquid-crystalline medium and liquid-crystal display MERCK PATENT GMBH (DE) 2020-08-11 US disclosed
US-10465115-B2 Cinnamic acid derivatives MERCK PATENT GMBH (DE) 2019-11-05 US disclosed
US-20190300791-A1 ADDITIVES FOR LIQUID CRYSTAL MIXTURES MERCK PATENT GMBH (DE) 2019-10-03 US disclosed
US-20190241809-A1 COMPOUNDS FOR THE HOMEOTROPIC ALIGNMENT OF LIQUID-CRYSTALLINE MEDIA MERCK PATENT GMBH (DE) 2019-08-08 US disclosed
US-20190153320-A1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2019-05-23 US disclosed
US-9944416-B2 Filling device and use thereof for dispensing a fluid MERCK PATENT GMBH (DE) 2018-04-17 US disclosed
US-20170121606-A1 POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS GMBH, MERCK PATENT (DE) 2017-05-04 US disclosed
US-20170037315-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2017-02-09 US disclosed
US-20150240159-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL COMPOSITION AND OPTICAL DEVICE JNC CORPORATION (JP) 2015-08-27 US disclosed
US-20150240159-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL COMPOSITION AND OPTICAL DEVICE JNC CORPORATION (JP) 2015-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11718791-B2 Polymerisable compounds and the use thereof in liquid-crystal displays VCL, ILK, LCP1 CYP11B1 4179/4885CYP11B2 3930/4885CETP 3418/4885
US-20220127532-A1 POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS LPXN, VCL, LCP1 CYP11B1 3931/4885CYP11B2 3942/4885CETP 3827/4885
US-10465115-B2 Cinnamic acid derivatives RCC1, LSS, C1S CYP11B1 2042/4885CYP11B2 2226/4885CETP 2224/4885
US-11685863-B2 Polymerisable compounds and the use thereof in liquid-crystal displays LPXN, VCL, LCP1 CYP11B1 3931/4885CYP11B2 3942/4885CETP 3827/4885
US-20230068853-A1 LIQUID CRYSTAL MIXTURE AND LIQUID CRYSTAL DISPLAY CXCR1, PYM1, F11 CYP11B1 403/4885CYP11B2 613/4885CETP 1723/4885
US-11312909-B2 Polymerizable compounds and the use thereof in liquid-crystal displays VCL, LCP1, MAP1LC3C CYP11B1 4468/4885CYP11B2 4388/4885CETP 2965/4885
US-20170121606-A1 POLYMERIZABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS VCL, LCP1, MAP1LC3C CYP11B1 4552/4885CYP11B2 4457/4885CETP 2851/4885
US-20190241809-A1 COMPOUNDS FOR THE HOMEOTROPIC ALIGNMENT OF LIQUID-CRYSTALLINE MEDIA NEFM, MDN1, VCL CYP11B1 3433/4885CYP11B2 3609/4885CETP 3476/4885
US-20150240159-A1 OPTICALLY ISOTROPIC LIQUID CRYSTAL COMPOSITION AND OPTICAL DEVICE SCO2, CNOT1, LEO1 CYP11B1 1012/4885CYP11B2 1169/4885CETP 3928/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.