Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | AR | P10275 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12997399 | 0.86 | AKR1C3 (0.41) | PTGS2PTGS1RPS6KA3CYP2C19 | |
| SCHEMBL13368801 | 0.79 | TAAR1 (0.36) | PTGS2CYP11B1CYP11B2LMNATDP1 | |
| SCHEMBL8192072 | 0.78 | ACHE (0.43) | ACHEPTGS2PTGS1RPS6KA3KDM4E | |
| SCHEMBL16258106 | 0.78 | ACHE (0.43) | ACHEPTGS2PTGS1RPS6KA3KDM4E | |
| SCHEMBL13614626 | 0.78 | ACHE (0.43) | ACHEPTGS2PTGS1RPS6KA3KDM4E | |
| SCHEMBL10018705 | 0.78 | ACHE (0.43) | ACHEPTGS2PTGS1RPS6KA3KDM4E | |
| SCHEMBL10014228 | 0.78 | ACHE (0.43) | ACHEPTGS2PTGS1RPS6KA3KDM4E | |
| SCHEMBL13799255 | 0.77 | CA1 (0.36) | ACHEPTGS2PTGS1RPS6KA3LMNA | |
| SCHEMBL10441525 | 0.77 | SELL (0.33) | PTGS2ALDH1A1NFE2L2 | |
| SCHEMBL13636907 | 0.76 | RARB (0.42) | CYP11B1HSD17B10MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2714843-B1 | LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY DEVICE | MERCK PATENT GMBH (DE) | 2016-12-21 | — | — | EP | disclosed |
| EP-2708587-A1 | Liquid crystal medium and liquid crystal display | Merck Patent GmbH (DE) | 2014-03-19 | — | — | EP | disclosed |
| EP-2116522-A1 | PENTACYCLIC LIQUID CRYSTAL COMPOUND HAVING CF<SB>2</SB>O BONDING GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY | Chisso Corporation (JP) | 2009-11-11 | — | — | EP | disclosed |
| EP-2100944-A1 | Liquid crystal medium and liquid crystal display | MERCK PATENT GmbH (DE) | 2009-09-16 | — | — | EP | disclosed |
| EP-1620527-B1 | LIQUID CRYSTAL COMPOSITION FOR USE IN BISTABLE LIQUID CRYSTAL DEVICES | MERCK PATENT GMBH (DE) | 2007-09-26 | — | — | EP | disclosed |