Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13615127 | 0.74 | ALDH1A1 (0.53) | TSHRMAPTPOLBALDH1A1KDM4E | |
| SCHEMBL13614998 | 0.74 | HSD17B10 (0.36) | MAPTPOLBALDH1A1KDM4EHSD17B10 | |
| SCHEMBL4391092 | 0.72 | KCNA3 (0.39) | ALDH1A1HPGDLMNA | |
| SCHEMBL2570228 | 0.71 | DYRK1A (0.42) | ALDH1A1KDM4EHSD17B10SMN1; SMN2HPGD | |
| SCHEMBL13615350 | 0.69 | TYK2 (0.41) | TSHRPOLBALDH1A1KDM4EHSD17B10 | |
| SCHEMBL10525830 | 0.65 | GAA (0.38) | TSHRMAPTPOLBNPSR1SMN1; SMN2 | |
| SCHEMBL12292136 | 0.64 | HSD17B10 (0.44) | POLBALDH1A1HSD17B10LMNAGAA | |
| SCHEMBL23352278 | 0.63 | NPSR1 (0.43) | TSHRALDH1A1KDM4ENPSR1SMN1; SMN2 | |
| SCHEMBL28701055 | 0.63 | TSHR (0.61) | TSHRMAPTPOLBALDH1A1KDM4E | |
| SCHEMBL12292129 | 0.62 | HSD17B10 (0.43) | MAPTPOLBALDH1A1HSD17B10SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141065-A2 | (1,2-BENZISOTHIAZOL-3-YL)(THIO)CARBAMATES AND (1,2-BENZISOTHIAZOL-3-YL)(THIO)OXAMATES AND THE OXIDATION FORMS THEREOF FOR USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2009-11-26 | — | — | WO | disclosed |