Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | NCF1 | P14598 | 5/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2573400 | 0.82 | HSD17B10 (0.48) | HSD17B10LMNAMAPTNPSR1L3MBTL1 | |
| SCHEMBL13615462 | 0.78 | LMNA (0.39) | HSD17B10LMNAMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL12322057 | 0.77 | IKBKB (0.32) | IKBKBKDM1AMAPTNPSR1L3MBTL1 | |
| SCHEMBL4391092 | 0.74 | KCNA3 (0.39) | KCNA3PKMLMNAALDH1A1 | |
| SCHEMBL13615001 | 0.74 | TSHR (0.42) | HSD17B10LMNAMAPTNPSR1ALDH1A1 | |
| SCHEMBL11090264 | 0.72 | ALDH1A1 (0.49) | HSD17B10LMNAMAPTNPSR1L3MBTL1 | |
| SCHEMBL10996068 | 0.72 | LMNA (0.41) | HSD17B10PKMLMNAMAPTALDH1A1 | |
| SCHEMBL2417806 | 0.71 | SMN1; SMN2 (0.33) | LMNAMAPTL3MBTL1KDM4E | |
| SCHEMBL23352277 | 0.71 | CYP1A2 (0.44) | IKBKBLMNAKDM1AMAPTNCF1 | |
| SCHEMBL2564355 | 0.67 | RET (0.43) | LMNAALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141065-A2 | (1,2-BENZISOTHIAZOL-3-YL)(THIO)CARBAMATES AND (1,2-BENZISOTHIAZOL-3-YL)(THIO)OXAMATES AND THE OXIDATION FORMS THEREOF FOR USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2009-11-26 | — | — | WO | disclosed |
| EP-2123159-A1 | (1,2-Benzisothiazol-3-yl)(thio)carbamates and (1,2-Benzisothiazol-3-yl)(thio)oxamates and their oxidation forms as pesticides | Bayer CropScience AG (DE) | 2009-11-25 | — | — | EP | disclosed |