Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2570228 | 0.82 | DYRK1A (0.42) | KMT2AALDH1A1GAASMN1; SMN2MEN1 | |
| SCHEMBL12303025 | 0.78 | KMT2A (0.51) | KMT2APOLBALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL12292136 | 0.75 | HSD17B10 (0.44) | KMT2APOLBALDH1A1GAAMEN1 | |
| SCHEMBL12292139 | 0.71 | HSD17B10 (0.41) | KMT2APOLBALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL13615001 | 0.70 | TSHR (0.42) | POLBALDH1A1GAAHTTSMN1; SMN2 | |
| SCHEMBL11176848 | 0.70 | KMT2A (0.72) | KMT2APOLBALDH1A1GAAHTT | |
| SCHEMBL12292142 | 0.70 | HSD17B10 (0.40) | KMT2APOLBALDH1A1GAAMEN1 | |
| SCHEMBL31154113 | 0.69 | HSD17B10 (0.49) | KMT2APOLBALDH1A1GAAHTT | |
| SCHEMBL4385529 | 0.68 | HPGD (0.44) | KMT2AHTTSMN1; SMN2MEN1HSD17B10 | |
| SCHEMBL13615748 | 0.68 | LMNA (0.56) | KMT2APOLBALDH1A1GAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009141065-A2 | (1,2-BENZISOTHIAZOL-3-YL)(THIO)CARBAMATES AND (1,2-BENZISOTHIAZOL-3-YL)(THIO)OXAMATES AND THE OXIDATION FORMS THEREOF FOR USE AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2009-11-26 | — | — | WO | disclosed |