Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.43 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 2/20 | 0.43 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.43 |
| ▸ | P2RY2 | P41231 | 1/20 | 0.42 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.42 |
| ▸ | P2RY6 | Q15077 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18522216 | 0.87 | PRMT6 (0.46) | PRMT6P2RY12ADORA1 | |
| SCHEMBL13615620 | 0.87 | PRMT6 (0.41) | PRMT6ADORA2AADORA2BP2RY12 | |
| SCHEMBL14303666 | 0.86 | PRMT6 (0.45) | PRMT6P2RY12ADORA1 | |
| SCHEMBL21759030 | 0.83 | PRMT6 (0.45) | PRMT6P2RY12ADORA1 | |
| SCHEMBL1582757 | 0.80 | MEN1 (0.63) | ADORA2AADORA2BADORA1ADORA3TP53 | |
| SCHEMBL1582760 | 0.80 | MEN1 (0.63) | ADORA2AADORA2BADORA1ADORA3TP53 | |
| SCHEMBL19841206 | 0.80 | MEN1 (0.63) | ADORA2AADORA2BADORA1ADORA3TP53 | |
| SCHEMBL29602480 | 0.80 | MEN1 (0.63) | ADORA2AADORA2BADORA1ADORA3TP53 | |
| SCHEMBL20454454 | 0.80 | MEN1 (0.63) | ADORA2AADORA2BADORA1ADORA3TP53 | |
| SCHEMBL12963332 | 0.80 | ADORA1 (0.58) | ADORA2AADORA2BP2RY12ADORA1ADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143369-A2 | METHOD OF PREPARING NUCLEOSIDES AND ANALOGS THEREOF WITHOUT USING CHROMATOGRAPHY | ISIS PHARMACEUTICALS, INC. (US) | 2009-11-26 | — | — | WO | disclosed |