Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.39 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.38 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13615540 | 0.87 | PRMT6 (0.46) | PRMT6ADORA2AADORA2BP2RY12 | |
| SCHEMBL12306566 | 0.83 | PRMT6 (0.43) | PRMT6ADORA2AADORA2BP2RY12 | |
| SCHEMBL12306554 | 0.83 | PRMT6 (0.43) | PRMT6ADORA2AADORA2BP2RY12 | |
| SCHEMBL12306622 | 0.82 | PRMT6 (0.43) | PRMT6P2RY12 | |
| SCHEMBL12852439 | 0.81 | PRMT6 (0.39) | PRMT6P2RY12BMPR1B | |
| SCHEMBL13615887 | 0.80 | P2RY6 (0.43) | — | |
| SCHEMBL12852444 | 0.80 | PRMT6 (0.39) | PRMT6ADORA2AADORA2BP2RY12BMPR1B | |
| SCHEMBL12851697 | 0.80 | P2RY12 (0.41) | PRMT6ADORA2AADORA2BP2RY12BMPR1B | |
| SCHEMBL12851646 | 0.80 | P2RY12 (0.41) | PRMT6ADORA2AADORA2BP2RY12BMPR1B | |
| SCHEMBL14364914 | 0.80 | PRMT6 (0.47) | PRMT6P2RY12BMPR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009143369-A2 | METHOD OF PREPARING NUCLEOSIDES AND ANALOGS THEREOF WITHOUT USING CHROMATOGRAPHY | ISIS PHARMACEUTICALS, INC. (US) | 2009-11-26 | — | — | WO | disclosed |