SCHEMBL13615627

SCHEMBL13615627

CC(C)C1c2ccccc2N(C)c2ccccc21

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC5 Q9UQL6 1/20 0.46
ACHE P22303 5/20 0.44
HTR2A P28223 3/20 0.43
HTR2C P28335 2/20 0.43
HRH1 P35367 2/20 0.43
ADRA2A P08913 1/20 0.43
ADRA2B P18089 1/20 0.43
ADRA2C P18825 1/20 0.43
SLC6A2 P23975 1/20 0.43
SLC6A4 P31645 1/20 0.43
ADRA1A P35348 1/20 0.43
HTR2B P41595 1/20 0.43
KCNH2 Q12809 1/20 0.43
MAOA P21397 1/20 0.40
GPR3 P46089 1/20 0.38
CHEK1 O14757 1/20 0.38
AURKA O14965 1/20 0.38
DAPK3 O43293 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2490138 0.84 MEN1 (0.42) HDAC4HDAC7HDAC5ACHEEGFR
SCHEMBL13615629 0.78 MAPT (0.42) HTR2CADRA2AADRA2BADRA2CSLC6A2
SCHEMBL3797401 0.77 HDAC4 (0.52) HDAC4HDAC7HDAC5ACHEHTR2A
SCHEMBL12591779 0.76 HRH1 (0.53) HDAC4HDAC7HDAC5ACHEHTR2A
SCHEMBL20094217 0.75 HDAC4 (0.55) HDAC4HDAC7HDAC5ACHEHTR2A
SCHEMBL29925103 0.75 HDAC4 (0.50) HDAC4HDAC7HDAC5ACHEHTR2A
SCHEMBL1105797 0.75 HDAC4 (0.50) HDAC4HDAC7HDAC5ACHEHTR2A
SCHEMBL15314698 0.75 HDAC4 (0.50) HDAC4HDAC7HDAC5ACHEHTR2A
SCHEMBL13068847 0.73 HDAC4 (0.48) HDAC4HDAC7HDAC5ACHEHTR2A
SCHEMBL17187194 0.73 HDAC4 (0.48) HDAC4HDAC7HDAC5ACHEHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240208929-A1 HYDROXYPYRIDINE HSD17B13 INHIBITORS AND USES THEREOF INIPHARM, INC. 2024-06-27 US disclosed
US-11758809-B2 Compound, display panel, and display apparatus Shanghai Tianma AM-OLED Co., Ltd. (CN) 2023-09-12 US disclosed
US-20200140416-A1 COMPOUND, OLED DISPLAY PANEL AND ELECTRONIC DEVICE WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2020-05-07 US disclosed
US-20200131144-A1 AMINE OR (THIO)AMIDE CONTAINING LXR MODULATORS PHENEX-FXR GMBH (DE) 2020-04-30 US disclosed
US-20090273277-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090273277-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OCIAD1, ORMDL3, CHRM2 HDAC4 4481/4885HDAC7 4563/4885HDAC5 4658/4885
US-20240208929-A1 HYDROXYPYRIDINE HSD17B13 INHIBITORS AND USES THEREOF HSD17B3, HSD17B1, HSD17B13 HDAC4 940/4885HDAC7 761/4885HDAC5 483/4885
US-20200140416-A1 COMPOUND, OLED DISPLAY PANEL AND ELECTRONIC DEVICE OCIAD2, OCIAD1, EED HDAC4 4753/4885HDAC7 4732/4885HDAC5 4862/4885
US-20200131144-A1 AMINE OR (THIO)AMIDE CONTAINING LXR MODULATORS NR1H2, NR1H3, NR1H4 HDAC4 798/4885HDAC7 722/4885HDAC5 685/4885
US-11758809-B2 Compound, display panel, and display apparatus C1S, C3AR1, DRD3 HDAC4 4721/4885HDAC7 4785/4885HDAC5 4726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.