SCHEMBL1105797

SCHEMBL1105797

CC1c2ccccc2N(C)c2ccccc21

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 1/20 0.50
HDAC7 Q8WUI4 1/20 0.50
HDAC5 Q9UQL6 1/20 0.50
ACHE P22303 5/20 0.48
HTR2A P28223 2/20 0.47
HTR2C P28335 2/20 0.47
HRH1 P35367 2/20 0.47
ADRA2A P08913 1/20 0.47
ADRA2B P18089 1/20 0.47
ADRA2C P18825 1/20 0.47
SLC6A2 P23975 1/20 0.47
SLC6A4 P31645 1/20 0.47
ADRA1A P35348 1/20 0.47
HTR2B P41595 1/20 0.47
KCNH2 Q12809 1/20 0.47
GPR3 P46089 1/20 0.47
MAOA P21397 1/20 0.44
CHEK1 O14757 1/20 0.41
AURKA O14965 1/20 0.41
DAPK3 O43293 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29925103 1.00 HDAC4 (0.50) HDAC4HDAC7HDAC5ACHEHTR2A
Iodide SCHEMBL28367716 0.98 HDAC4 (0.48) HDAC4HDAC7HDAC5ACHEHTR2A
SCHEMBL20991138 0.84 HDAC4 (0.40) HDAC4HDAC7HDAC5ACHEHTR2A
SCHEMBL29557464 0.82 BRD4 (0.49) HDAC4HDAC7HDAC5ACHEHTR2A
SCHEMBL769455 0.82 BRD4 (0.49) HDAC4HDAC7HDAC5ACHEHTR2A
SCHEMBL11438801 0.82 EGFR (0.49) HDAC4HDAC7HDAC5ACHEHTR2A
SCHEMBL3797401 0.82 HDAC4 (0.52) HDAC4HDAC7HDAC5ACHEHTR2A
SCHEMBL6055686 0.81 GPR3 (0.40) HDAC4HDAC7HDAC5ACHEHTR2A
SCHEMBL20094217 0.80 HDAC4 (0.55) HDAC4HDAC7HDAC5ACHEHTR2A
SCHEMBL15314698 0.80 HDAC4 (0.50) HDAC4HDAC7HDAC5ACHEHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104193671-A Purification method of coal tar fine carbazole SHANXI YONGDONG CHEMICAL CO LTD 2014-12-10 CN claimed
WO-2024080787-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2024-04-18 WO disclosed
US-11785841-B2 Compound, display panel and display apparatus WUHAN TIANMA MICROELECTRONICS CO., LTD. (CN) 2023-10-10 US disclosed
US-11780831-B2 Compound, display panel and display apparatus Shanghai Tianma AM-OLED Co., Ltd. (CN) 2023-10-10 US disclosed
US-11691991-B2 Compound, a display panel and a display device Shanghai Tianma AM-OLED Co., Ltd. (CN) 2023-07-04 US disclosed
US-11667618-B2 Azulene ring-containing compound, its use, and an organic photoelectric device including the same WUHAN TIANMA MICRO-ELECTRONICS CO., LTD. (CN) 2023-06-06 US disclosed
CN-111276620-B Organic light emitting diode and organic light emitting device having the same 乐金显示有限公司 2023-02-07 CN disclosed
US-11515485-B2 Organic light emitting diode and organic light emitting device having the same LG DISPLAY CO., LTD. (KR) 2022-11-29 US disclosed
CN-115304592-A Diazosulfide heat shock delayed fluorescent material and preparation method thereof 兰州大学 2022-11-08 CN disclosed
CN-110699677-B Self-assembled film of methylacridine salt on carbon steel surface and corrosion resistance 威海海洋生物医药产业技术研究院有限公司 2022-07-15 CN disclosed
US-20090226954-A1 Labeling of target molecules, identification of organelles and other applications, novel compositions, methods and kits ENZO LIFE SCIENCES, INC. 2009-09-10 US disclosed
US-20090226954-A1 Labeling of target molecules, identification of organelles and other applications, novel compositions, methods and kits ENZO LIFE SCIENCES, INC. 2009-09-10 US disclosed
US-7569695-B2 Cyanine dyes substituted by electrophilic groups and/or nucleophilic groups including merocyanine, methine, oxazoline, oxonol, selenazole fluorescent, imidazoline, quinoline, indole, reactive and cationic dyes; labeling reagents for proteins and nucleic acids; genetic probes; amplification; hybridization ENZO LIFE SCIENCES, INC. (US) 2009-08-04 US disclosed
US-7569695-B2 Cyanine dyes substituted by electrophilic groups and/or nucleophilic groups including merocyanine, methine, oxazoline, oxonol, selenazole fluorescent, imidazoline, quinoline, indole, reactive and cationic dyes; labeling reagents for proteins and nucleic acids; genetic probes; amplification; hybridization ENZO LIFE SCIENCES, INC. (US) 2009-08-04 US disclosed
WO-2009014513-A1 NOVEL DYES FOR THE DETECTION OR QUANTIFICATION OF DESIRABLE TARGET MOLECULES ENZO LIFE SCIENCES, INC. (US) 2009-01-29 WO disclosed
EP-0838463-B1 Squarylium compound and optical information recording medium using the same KYOWA HAKKO KOGYO KK (JP) 2002-03-27 EP disclosed
EP-0838463-A2 Squarylium compound and optical information recording medium using the same KYOWA HAKKO KOGYO CO., LTD. (JP) 1998-04-29 EP disclosed
US-5660970-A STORAGE STABILITY; COMPACT DISKS KYOWA HAKKO KOGYO CO., LTD. (JP) 1997-08-26 US disclosed
US-5391741-A Can be vacuum deposited; storage stability, high absorbance in near infrared KYOWA HAKKO KOGYO CO., LTD. (JP) 1995-02-21 US disclosed
EP-0568877-A1 Squarylium compounds and optical information recording medium using the same KYOWA HAKKO KOGYO CO., LTD. (JP) 1993-11-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090226954-A1 Labeling of target molecules, identification of organelles and other applications, novel compositions, methods and kits SSBP1, IMMT, DNAJA3 HDAC4 3906/4885HDAC7 3926/4885HDAC5 2631/4885
US-11667618-B2 Azulene ring-containing compound, its use, and an organic photoelectric device including the same CCNE2, CCNE1, ESR1 HDAC4 4791/4885HDAC7 4747/4885HDAC5 4578/4885
US-11691991-B2 Compound, a display panel and a display device BROX, BRSK1, BRSK2 HDAC4 2284/4885HDAC7 2255/4885HDAC5 1654/4885
US-11785841-B2 Compound, display panel and display apparatus C1S, CDK20, CEP170 HDAC4 4611/4885HDAC7 4543/4885HDAC5 4587/4885
US-11780831-B2 Compound, display panel and display apparatus C1S, DRD1, DRD3 HDAC4 3944/4885HDAC7 4211/4885HDAC5 4387/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.