Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.57 |
| ▸ | CA2 | P00918 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14898425 | 0.94 | ESR1 (0.52) | CA1CA2TDP1CA12CA7 | |
| SCHEMBL8408221 | 0.93 | MAPT (0.50) | CA1CA2TDP1CA12CA7 | |
| SCHEMBL12920511 | 0.86 | ESR1 (0.66) | CA1CA2TDP1CA12CA7 | |
| SCHEMBL12146851 | 0.86 | MAPT (0.47) | CA1CA2TDP1CA12CA7 | |
| SCHEMBL513612 | 0.86 | TDP1 (0.61) | CA1CA2TDP1CA12CA7 | |
| SCHEMBL15397149 | 0.86 | MAPT (0.54) | CA1CA2TDP1CA12CA7 | |
| SCHEMBL27468716 | 0.85 | LOXL2 (0.56) | CA1CA2CA12CA7CA9 | |
| SCHEMBL12441833 | 0.84 | HPGD (0.45) | CA1CA2TDP1CA12CA7 | |
| SCHEMBL514607 | 0.84 | CA1 (0.44) | CA1CA2TDP1CA12CA7 | |
| SCHEMBL514974 | 0.84 | LMNA (0.67) | CA1CA2TDP1CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090281226-A1 | PROCESS FOR MAKING NANOCOMPOSITES | E. I. DU PONT DE NEMOURS AND COMPANY | 2009-11-12 | — | — | US | disclosed |