SCHEMBL13615764

SCHEMBL13615764

c1ccc2c(c1)c1ccc(-c3cnccn3)cc1c1c3ccccc3c3ccc(-c4cnccn4)cc3c21

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.42
PIK3CA P42336 1/20 0.42
PIK3CB P42338 1/20 0.42
PI4KA P42356 1/20 0.42
PIK3CG P48736 1/20 0.42
PI4KB Q9UBF8 1/20 0.42
PIM1 P11309 4/20 0.41
ALOX5AP P20292 2/20 0.41
FEN1 P39748 2/20 0.41
PIM2 Q9P1W9 4/20 0.40
PIM3 Q86V86 2/20 0.40
CHEK1 O14757 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP19A1 P11511 1/20 0.40
CYP2C9 P11712 1/20 0.40
CYP2C19 P33261 1/20 0.40
CYP3A4 P08684 1/20 0.36
METAP2 P50579 1/20 0.36
CYP2A6 P11509 1/20 0.36
ABL1 P00519 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13615946 1.00 PIK3CD (0.42) PIK3CDPIK3CAPIK3CBPI4KAPIK3CG
SCHEMBL13615874 0.93 PIK3CD (0.46) PIK3CDPIK3CAPIK3CBPI4KAPIK3CG
SCHEMBL17426587 0.91 PIK3CD (0.45) PIK3CDPIK3CAPIK3CBPI4KAPIK3CG
SCHEMBL13615897 0.81 PRMT5 (0.47) PIK3CDPIK3CAPI4KAPIK3CGPI4KB
SCHEMBL13615744 0.81 PRMT5 (0.47) PIK3CDPIK3CAPI4KAPIK3CGPI4KB
SCHEMBL13615929 0.81 PRMT5 (0.47) PIK3CDPIK3CAPI4KAPIK3CGPI4KB
SCHEMBL19768145 0.79 PIK3CD (0.40) PIK3CDPIK3CAPIK3CBPI4KAPIK3CG
SCHEMBL28714190 0.78 MAPT (0.41) PIK3CDPIK3CAPIK3CBPI4KAPIK3CG
SCHEMBL24741395 0.78 PRMT5 (0.45) PIK3CDPIK3CAPI4KAPIK3CGPI4KB
SCHEMBL13615855 0.77 KDM4E (0.50) PIK3CDPIK3CAPI4KAPIK3CGPI4KB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090273278-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-11-05 US disclosed
US-20090273278-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-11-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090273278-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same OCIAD1, OCIAD2, ORMDL3 PIK3CD 1851/4885PIK3CA 3332/4885PIK3CB 3812/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.