SCHEMBL17426587

SCHEMBL17426587

c1ccc2c(c1)c1ccccc1c1cc(-c3cnccn3)ccc21

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PIK3CD O00329 1/20 0.45
PIK3CA P42336 1/20 0.45
PIK3CB P42338 1/20 0.45
PI4KA P42356 1/20 0.45
PIK3CG P48736 1/20 0.45
PI4KB Q9UBF8 1/20 0.45
PIM1 P11309 4/20 0.44
PIM2 Q9P1W9 4/20 0.43
ALOX5AP P20292 2/20 0.43
FEN1 P39748 2/20 0.43
CYP2D6 P10635 1/20 0.42
CYP19A1 P11511 1/20 0.42
CYP2C9 P11712 1/20 0.42
CYP2C19 P33261 1/20 0.42
PIM3 Q86V86 2/20 0.42
CHEK1 O14757 1/20 0.42
METAP2 P50579 1/20 0.39
CYP2A6 P11509 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP11B1 P15538 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13615764 0.91 PIK3CD (0.42) PIK3CDPIK3CAPIK3CBPI4KAPIK3CG
SCHEMBL13615946 0.91 PIK3CD (0.42) PIK3CDPIK3CAPIK3CBPI4KAPIK3CG
SCHEMBL13615874 0.87 PIK3CD (0.46) PIK3CDPIK3CAPIK3CBPI4KAPIK3CG
SCHEMBL19768145 0.87 PIK3CD (0.40) PIK3CDPIK3CAPIK3CBPI4KAPIK3CG
SCHEMBL19768012 0.83 PIM1 (0.39) PIK3CDPIK3CAPIK3CBPI4KAPIK3CG
SCHEMBL28714190 0.82 MAPT (0.41) PIK3CDPIK3CAPIK3CBPI4KAPIK3CG
SCHEMBL28163146 0.80 GABRP (0.51) PIM1METAP2MAPT
SCHEMBL17229021 0.79 KDM4E (0.52) PIK3CDPIK3CAPI4KAPIK3CGPI4KB
SCHEMBL13321297 0.79 KDM4E (0.52) PIK3CDPIK3CAPI4KAPIK3CGPI4KB
SCHEMBL4144929 0.78 CYP11B1 (0.58) PIK3CDPIK3CAPIK3CBPI4KAPIK3CG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230134350-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORP. (TW) 2023-05-04 US disclosed
US-20230134350-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME LUMINESCENCE TECHNOLOGY CORP. (TW) 2023-05-04 US disclosed
US-10305041-B2 Organic light-emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2019-05-28 US disclosed
US-9666807-B2 Organic light emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-05-30 US disclosed
US-9666807-B2 Organic light emitting device SAMSUNG DISPLAY CO., LTD. (KR) 2017-05-30 US disclosed
US-9401484-B2 Organic light-emitting device having increased electron transport ability of an electron transport region SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-26 US disclosed
US-9401484-B2 Organic light-emitting device having increased electron transport ability of an electron transport region SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-26 US disclosed
US-20160133844-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-05-12 US disclosed
US-20160133844-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-05-12 US disclosed
US-20160028017-A1 ORGANIC LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-28 US disclosed
US-20160028017-A1 ORGANIC LIGHT EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-28 US disclosed
US-20160013427-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-14 US disclosed
US-20160013427-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-14 US disclosed
US-20160013430-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-14 US disclosed
US-20160013430-A1 ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2016-01-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230134350-A1 ORGANIC COMPOUND AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME OR10J3, ODC1, OTC PIK3CD 4574/4885PIK3CA 4439/4885PIK3CB 4684/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.