Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.69 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | SCN1A | P35498 | 3/20 | 0.63 |
| ▸ | SCN2A | Q99250 | 3/20 | 0.63 |
| ▸ | SCN3A | Q9NY46 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.63 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.54 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.54 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.51 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.51 |
| ▸ | HTR3B | O95264 | 1/20 | 0.51 |
| ▸ | HTR3A | P46098 | 1/20 | 0.51 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.51 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11976987 | 0.86 | MAPT (0.69) | MAPTALDH1A1CYP2C9CYP2C19POLB | |
| SCHEMBL21541871 | 0.86 | MAPT (0.69) | MAPTALDH1A1CYP2C9CYP2C19POLB | |
| SCHEMBL11977004 | 0.85 | MAPT (0.65) | MAPTALDH1A1CYP2C9CYP2C19POLB | |
| SCHEMBL12591313 | 0.84 | SCN1A (0.67) | MAPTALDH1A1SCN1ASCN2ASCN3A | |
| SCHEMBL8621135 | 0.82 | MAPT (1.00) | MAPTALDH1A1CYP2C9CYP2C19POLB | |
| SCHEMBL8551383 | 0.80 | CARM1 (0.60) | POLBSCN1ASCN2ASCN3AKMT2A | |
| SCHEMBL10306603 | 0.80 | KMT2A (0.66) | MAPTALDH1A1CYP2C9CYP2C19POLB | |
| SCHEMBL1839704 | 0.79 | KMT2A (0.97) | ALDH1A1SCN1ASCN2ASCN3AKMT2A | |
| Hydrochloric Acid SCHEMBL8552406 | 0.79 | MEN1 (0.61) | POLBSCN1ASCN2ASCN3AKMT2A | |
| SCHEMBL27949304 | 0.79 | ALDH1A1 (0.63) | MAPTALDH1A1CYP2C19SCN1ASCN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8324225-B2 | Pyrrolopyrimidine compounds and their uses | NOVARTIS AG (CH) | 2012-12-04 | — | — | US | disclosed |
| US-20090318441-A1 | Pyrrolopyrimidine Compounds and Their Uses | ASTEX THERAPEUTICS LTD. | 2009-12-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090318441-A1 | Pyrrolopyrimidine Compounds and Their Uses | PRKDC, TK2, PNKP | MAPT 2154/4885ALDH1A1 1780/4885CYP2C9 4093/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.