Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 1.00 |
| ▸ | POLB | P06746 | 4/20 | 1.00 |
| ▸ | CYP2C9 | P11712 | 1/20 | 1.00 |
| ▸ | CYP2C19 | P33261 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.78 |
| ▸ | CRHBP | P24387 | 1/20 | 0.61 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | HTR1A | P08908 | 1/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | SCN1A | P35498 | 1/20 | 0.48 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.48 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8551863 | 0.82 | MAPT (0.69) | MAPTPOLBCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL21541871 | 0.82 | MAPT (0.69) | MAPTPOLBCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL13616264 | 0.82 | MAPT (0.70) | MAPTPOLBCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL23783139 | 0.82 | MAPT (0.69) | MAPTPOLBCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL27950762 | 0.82 | MAPT (0.70) | MAPTPOLBCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL23300904 | 0.82 | MAPT (0.69) | MAPTPOLBCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL11976987 | 0.82 | MAPT (0.69) | MAPTPOLBCYP2C9CYP2C19ALDH1A1 | |
| Hydrochloric Acid SCHEMBL8555329 | 0.81 | MAPT (0.68) | MAPTPOLBCYP2C9CYP2C19ALDH1A1 | |
| Hydrochloric Acid SCHEMBL6622524 | 0.80 | MAPT (0.67) | MAPTPOLBCYP2C9CYP2C19ALDH1A1 | |
| SCHEMBL6052363 | 0.80 | MAPT (0.66) | MAPTPOLBCYP2C9CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0871613-A1 | BENZYL PIPERIDINE DERIVATIVES AS PHARMACEUTICAL AGENTS | F. HOFFMANN-LA ROCHE AG (CH) | 1998-10-21 | — | — | EP | disclosed |
| WO-1996035666-A1 | BENZYL PIPERIDINE DERIVATIVES AS PHARMACEUTICAL AGENTS | F.HOFFMANN-LA ROCHE AG (CH) | 1996-11-14 | — | — | WO | disclosed |