Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.67 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.85 |
| ▸ | TSHR | P16473 | 5/20 | 0.79 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.79 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.79 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | BLM | P54132 | 2/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | THRB | P10828 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.67 |
| ▸ | PLG | P00747 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.65 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.65 |
| ▸ | GABRP | O00591 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL928332 | 1.00 | LMNA (0.85) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL23045133 | 0.96 | TSHR (0.86) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL4353642 | 0.96 | TSHR (0.86) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Hydrazine SCHEMBL28254323 | 0.96 | TSHR (0.86) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Azelaic Acid SCHEMBL28251822 | 0.96 | TSHR (0.86) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL10757174 | 0.92 | LMNA (0.85) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Glutarate SCHEMBL28219331 | 0.92 | SLC22A6 (0.85) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL8941691 | 0.92 | LMNA (1.00) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL4930 | 0.92 | LMNA (1.00) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL2244299 | 0.92 | LMNA (1.00) | LMNATSHRNFKB1PMP22SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 134 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114983982-B | Sustained-release type oral ulcer hydrogel ulcer patch | 浙江大学 | 2023-09-29 | — | — | CN | claimed |
| CN-114983982-A | Slow-release type dental ulcer hydrogel ulcer plaster | 浙江大学 | 2022-09-02 | — | — | CN | claimed |
| CN-108362891-B | Prednisone magnetic immuno-chemiluminescence detection kit and application thereof | 北京勤邦生物技术有限公司 | 2020-09-25 | — | — | CN | claimed |
| CN-110229579-A | A kind of environment friendly emulsion paint of formaldehyde degradation by photocatalytic oxidation process and preparation method thereof | 大连工业大学 | 2019-09-13 | — | — | CN | claimed |
| CN-109790255-A | Aqueous polymer dispersion and its purposes as solid black priming paint | 巴斯夫欧洲公司 | 2019-05-21 | — | — | CN | claimed |
| CN-109589945-A | A kind of formaldehyde scavenger and preparation method thereof | 郑州绿佳环保科技有限公司 | 2019-04-09 | — | — | CN | claimed |
| CN-105209528-B | Fire-retarded epoxy resin formulation and application thereof | 赫克塞尔合成有限公司 | 2019-04-02 | — | — | CN | claimed |
| CN-109337200-A | The application of nucleating agent VOC in reducing PP composite material | 成都金发科技新材料有限公司 | 2019-02-15 | — | — | CN | claimed |
| CN-108977407-A | A kind of preparation and application for the cadherins fusion protein functional modification tissue engineering bracket promoting vascularization | 南开大学 | 2018-12-11 | — | — | CN | claimed |
| CN-105524356-A | Polypropylene microporous membrane porosity conditioning agent, microporous membrane and preparation method thereof | UNIV HENAN NORMAL | 2016-04-27 | — | — | CN | claimed |
| CN-102603941-A | Preparation method of beta crystalline form polypropylene resin | CHINESE ACAD INST CHEMISTRY | 2012-07-25 | — | — | CN | claimed |
| CN-1829683-A | Mildronate, preparation method thereof and pharmaceutical composition based on mildronate | GRINDEKS JSC (LV) | 2006-09-06 | — | — | CN | claimed |
| JP-6212094-A | — | — | None | — | — | JP | disclosed |
| EP-3514194-B1 | AROMATIC POLYETHER MICROPARTICLES, METHOD FOR PRODUCING CURED RESIN PRODUCT, AND METHOD FOR PRODUCING CARBON-FIBER-REINFORCED COMPOSITE MATERIAL | SUMITOMO CHEMICAL CO (JP) | 2024-03-20 | — | — | EP | disclosed |
| CN-114983982-B | Sustained-release type oral ulcer hydrogel ulcer patch | 浙江大学 | 2023-09-29 | — | — | CN | disclosed |
| EP-3591110-B1 | NONWOVEN FABRIC | SUMITOMO CHEMICAL CO (JP) | 2023-04-12 | — | — | EP | disclosed |
| US-5662966-A | POLYESTERURETHANES USING DIMETHYLOLALKANE ACID MONOMERS | MITSUBISHI CHEMICAL CORPORATION (JP) | 1997-09-02 | — | — | US | disclosed |
| EP-0735069-A1 | Process for producing aqueous polyurethane coating and coat therefrom | Mitsubishi Chemical Corporation (JP) | 1996-10-02 | — | — | EP | disclosed |
| JP-H06212094-A | WATER-BASED OVER-PRINT VARNISH COMPOSITION | TOYO INK MFG CO LTD | 1994-08-02 | — | — | JP | disclosed |
| US-4088665-A | Process for the partial carbodiimidization of organic isocyanates | BAYER AKTIENGESELLSCHAFT (DT) | 1978-05-09 | — | — | US | disclosed |