Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 known ✓ | P23975 | 1/20 | 0.67 |
| ▸ | SLC6A3 known ✓ | Q01959 | 1/20 | 0.67 |
| ▸ | LMNA | P02545 | 4/20 | 0.85 |
| ▸ | TSHR | P16473 | 5/20 | 0.79 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.79 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.79 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.71 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.67 |
| ▸ | BLM | P54132 | 2/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.67 |
| ▸ | THRB | P10828 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 2/20 | 0.67 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.67 |
| ▸ | PLG | P00747 | 1/20 | 0.67 |
| ▸ | RECQL | P46063 | 1/20 | 0.67 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.65 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.65 |
| ▸ | GABRP | O00591 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL1361644 | 1.00 | LMNA (0.85) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL23045133 | 0.96 | TSHR (0.86) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Sebacic Acid SCHEMBL4353642 | 0.96 | TSHR (0.86) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Hydrazine SCHEMBL28254323 | 0.96 | TSHR (0.86) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Azelaic Acid SCHEMBL28251822 | 0.96 | TSHR (0.86) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL10757174 | 0.92 | LMNA (0.85) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Glutarate SCHEMBL28219331 | 0.92 | SLC22A6 (0.85) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL8941691 | 0.92 | LMNA (1.00) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL4930 | 0.92 | LMNA (1.00) | LMNATSHRNFKB1PMP22SLC22A6 | |
| Adipic Acid SCHEMBL2244299 | 0.92 | LMNA (1.00) | LMNATSHRNFKB1PMP22SLC22A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110698680-B | Self-healing sodium alginate/gelatin-based hydrogel material capable of spraying to form film | 四川大学 | 2022-09-02 | — | — | CN | claimed |
| CN-114395822-A | Preparation method of physical and chemical synergetic super-hydrophobic waterborne polyurethane film | 长春工业大学 | 2022-04-26 | — | — | CN | claimed |
| CN-108384428-B | Light-resistant antibacterial waterborne polyurethane coating and preparation method thereof | 唐山德生科技有限公司 | 2021-08-31 | — | — | CN | claimed |
| CN-112646114-A | Triplecene derivative modified polyurethane aqueous resin and preparation method thereof | 合众（佛山）化工有限公司 | 2021-04-13 | — | — | CN | claimed |
| CN-112625208-A | Tripolyindenone derivative modified waterborne polyurethane resin and preparation method thereof | 合众（佛山）化工有限公司 | 2021-04-09 | — | — | CN | claimed |
| CN-112210061-A | Preparation method of organic silicon modified castor oil based waterborne polyurethane film | 长春工业大学 | 2021-01-12 | — | — | CN | claimed |
| CN-111205726-A | Water-based acrylic acid water-resistant road marking paint and preparation method thereof | 王春林 | 2020-05-29 | — | — | CN | claimed |
| CN-106832138-B | Graphene-fluorine modified waterborne polyurethane resin and preparation method thereof | 合众（佛山）化工有限公司 | 2020-03-20 | — | — | CN | claimed |
| CN-110698692-A | Preparation method and application of self-healing sodium alginate/gelatin-based hydrogel material capable of spraying to form film | 四川大学 | 2020-01-17 | — | — | CN | claimed |
| CN-110698680-A | Self-healing sodium alginate/gelatin-based hydrogel material capable of spraying to form film | 四川大学 | 2020-01-17 | — | — | CN | claimed |
| US-20190134177-A1 | CONJUGATE FOR VACCINATION AGAINST TYPHOID COMPRISING CHEMICAL CONJUGATE OF VI POLYSACCHARIDE AND FLAGELLIN, A PROCESS FOR PRODUCING THE SAME AND A COMPOSITION COMPRISING THE CONJUGATE | NAT INSTITUTE OF IMMUNOLOGY (IN) | 2019-05-09 | — | — | US | claimed |
| WO-2017187448-A1 | A NOVEL CONJUGATE FOR VACCINATION AGAINST TYPHOID COMPRISING CHEMICAL CONJUGATE OF VI POLYSACCHARIDE AND FLAGELLIN, A PROCESS FOR PRODUCING THE SAME AND A COMPOSITION COMPRISING THE CONJUGATE | NATIONAL INSTITUTE OF IMMUNOLOGY (IN) | 2017-11-02 | — | — | WO | claimed |
| CN-86104458-A | With affinity chromatography purifying haemachrome and improvement haemachrome | — | 1987-07-01 | — | — | CN | claimed |
| US-12428517-B2 | Moisture curable polyurethane composition and laminate | TOKUYAMA CORPORATION (JP) | 2025-09-30 | — | — | US | disclosed |
| US-20250297145-A1 | SURFACE TOLERANT ADHESIVE | HUNTSMAN ADVANCED MATERIALS AMERICAS LLC | 2025-09-25 | — | — | US | disclosed |
| US-20250257162-A1 | CURABLE COMPOSITION, CURED BODY, LAMINATE, OPTICAL ARTICLE, LENS, AND EYEGLASSES | TOKUYAMA CORPORATION (JP) | 2025-08-14 | — | — | US | disclosed |
| EP-1582217-A1 | METHOD OF OBTAINING CONJUGATE VACCINES AND VACCINE COMPOSITIONS CONTAINING SAME | Instituto Finlay, Centro de Investigacion-Produccion de vacunas y sueros (CU) | 2005-10-05 | — | — | EP | disclosed |
| CN-1458950-A | Aldehyde emission reduction for dibenzylidene sorbitol clarified plastics | MILLIKEN & CO (US) | 2003-11-26 | — | — | CN | disclosed |
| US-20020119095-A1 | Chemotherapeutic agents conjugated to p97 and their methods of use in treating neurological tumours | GABATHULER REINHARD (CA) | 2002-08-29 | — | — | US | disclosed |
| WO-2002013843-A2 | CHEMOTHERAPEUTIC AGENTS CONJUGATED TO P97 AND THEIR METHODS OF USE IN TREATING NEUROLOGICAL TUMOURS | UNIVERSITY OF BRITISH COLUMBIA (CA) | 2002-02-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020119095-A1 | Chemotherapeutic agents conjugated to p97 and their methods of use in treating neurological tumours | SLC47A1, TMEM97, TUBA1C | SLC6A2 2081/4885SLC6A3 1718/4885LMNA 2121/4885 |
| US-20190134177-A1 | CONJUGATE FOR VACCINATION AGAINST TYPHOID COMPRISING CHEMICAL CONJUGATE OF VI POLYSACCHARIDE AND FLAGELLIN, A PROCESS FOR PRODUCING THE SAME AND A COMPOSITION COMPRISING THE CONJUGATE | TLR6, TLR5, TLR9 | SLC6A2 2942/4885SLC6A3 3210/4885LMNA 4686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.