Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 9/20 | 0.57 |
| ▸ | LPAR2 | Q9HBW0 | 8/20 | 0.57 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.57 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | PGD | P52209 | 1/20 | 0.38 |
| ▸ | TPI1 | P60174 | 1/20 | 0.38 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.37 |
| ▸ | LPAR4 | Q99677 | 1/20 | 0.37 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1650937 | 0.91 | LPAR3 (0.50) | LPAR3LPAR2LPAR1PGDTPI1 | |
| Urea SCHEMBL28528722 | 0.86 | LPAR3 (0.60) | LPAR3LPAR2LPAR1PGDTPI1 | |
| SCHEMBL22661363 | 0.84 | PGD (0.42) | LPAR3LPAR2LPAR1PGDTPI1 | |
| SCHEMBL27042244 | 0.83 | LPAR3 (0.76) | LPAR3LPAR2LPAR1LPAR5 | |
| SCHEMBL9233772 | 0.83 | LPAR3 (0.76) | LPAR3LPAR2LPAR1LPAR5 | |
| SCHEMBL28124639 | 0.83 | LPAR3 (0.76) | LPAR3LPAR2LPAR1LPAR5 | |
| SCHEMBL27042238 | 0.83 | LPAR3 (0.76) | LPAR3LPAR2LPAR1LPAR5 | |
| SCHEMBL6851142 | 0.83 | LPAR3 (0.76) | LPAR3LPAR2LPAR1LPAR5 | |
| SCHEMBL6033633 | 0.83 | LPAR3 (0.76) | LPAR3LPAR2LPAR1LPAR5 | |
| Propyl Phosphate SCHEMBL29926263 | 0.83 | LPAR3 (0.63) | LPAR3LPAR2LPAR1ENPP2LPAR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7615221-B2 | Compositions and methods for treating cancer | ONCOLOGIC, INC. (US) | 2009-11-10 | — | — | US | disclosed |