Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 8/20 | 0.50 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.50 |
| ▸ | LPAR1 | Q92633 | 4/20 | 0.50 |
| ▸ | PGD | P52209 | 1/20 | 0.41 |
| ▸ | TPI1 | P60174 | 2/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.37 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.37 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.37 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.37 |
| ▸ | PGK1 | P00558 | 1/20 | 0.35 |
| ▸ | PGK2 | P07205 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13616539 | 0.91 | LPAR3 (0.57) | LPAR3LPAR2LPAR1PGDTPI1 | |
| SCHEMBL22661363 | 0.88 | PGD (0.42) | LPAR3LPAR2LPAR1PGDTPI1 | |
| Urea SCHEMBL28528722 | 0.85 | LPAR3 (0.60) | LPAR3LPAR2LPAR1PGDTPI1 | |
| SCHEMBL4533846 | 0.81 | LPAR3 (0.50) | LPAR3LPAR2LPAR1PGK1PGK2 | |
| SCHEMBL11386950 | 0.79 | LPAR3 (0.48) | LPAR3LPAR2LPAR1PGK1PGK2 | |
| SCHEMBL16792076 | 0.79 | LPAR3 (0.54) | LPAR3LPAR2LPAR1 | |
| SCHEMBL1576717 | 0.79 | LPAR3 (0.64) | LPAR3LPAR2LPAR1TPI1CSNK2A2 | |
| SCHEMBL1574125 | 0.79 | LPAR3 (0.71) | LPAR3LPAR2LPAR1TPI1CSNK2A2 | |
| SCHEMBL1106834 | 0.79 | MVD (0.43) | LPAR3LPAR2LPAR1PGDTPI1 | |
| SCHEMBL14647819 | 0.79 | PLA2G2A (0.36) | LPAR3LPAR2LPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7927613-B2 | Pharmaceutical co-crystal compositions | UNIVERSITY OF SOUTH FLORIDA (US) | 2011-04-19 | — | — | US | disclosed |
| US-7790905-B2 | Pharmaceutical propylene glycol solvate compositions | MCNEIL-PPC, INC. (US) | 2010-09-07 | — | — | US | disclosed |