Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | GLA | P06280 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL274106 | 0.84 | ALOX15 (0.40) | ALOX15RECQLL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL279459 | 0.84 | ALOX15 (0.40) | ALOX15RECQLL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL274107 | 0.84 | ALOX15 (0.40) | ALOX15RECQLL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL13444916 | 0.82 | ALDH1A1 (0.38) | ALOX15RECQLL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL31329816 | 0.81 | ALOX15 (0.38) | ALOX15RECQLL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL23143393 | 0.76 | ALOX15 (0.36) | ALOX15RECQLL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL23143392 | 0.76 | ALOX15 (0.36) | ALOX15RECQLL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL6375896 | 0.74 | ALDH1A1 (0.41) | ALOX15RECQLL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL23030180 | 0.72 | CYP1A2 (0.39) | ALOX15RECQLL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL29882667 | 0.72 | CYP1A2 (0.39) | ALOX15RECQLL3MBTL1KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009135885-A1 | FUSED PYRAZINE COMPOUNDS USEFUL FOR THE TREATMENT OF DEGENERATIVE AND INFLAMMATORY DISEASES | GALAPAGOS NV (BE) | 2009-11-12 | — | — | WO | disclosed |