Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 12/20 | 0.63 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.58 |
| ▸ | HTR3A | P46098 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947433 | 0.87 | HTR4 (0.73) | HTR4TMEM97SIGMAR1HTR3A | |
| SCHEMBL30428794 | 0.87 | HTR4 (0.73) | HTR4TMEM97SIGMAR1HTR3A | |
| SCHEMBL30139058 | 0.87 | HTR4 (0.73) | HTR4TMEM97SIGMAR1HTR3A | |
| SCHEMBL3096608 | 0.87 | HTR4 (0.73) | HTR4TMEM97SIGMAR1HTR3A | |
| Hydrochloric Acid SCHEMBL7637431 | 0.86 | HTR4 (0.72) | HTR4TMEM97SIGMAR1HTR3A | |
| Hydrochloric Acid SCHEMBL29384867 | 0.86 | HTR4 (0.72) | HTR4TMEM97SIGMAR1HTR3A | |
| Hydrochloric Acid SCHEMBL10322633 | 0.86 | HTR4 (0.72) | HTR4TMEM97SIGMAR1HTR3A | |
| Hydrochloric Acid SCHEMBL7634797 | 0.86 | HTR4 (0.72) | HTR4TMEM97SIGMAR1HTR3A | |
| SCHEMBL3844694 | 0.84 | HTR4 (0.56) | HTR4TMEM97SIGMAR1HTR3A | |
| SCHEMBL3772860 | 0.84 | HTR4 (0.56) | HTR4TMEM97SIGMAR1HTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1960396-B1 | CARBAMATE COMPOUNDS AS 5-HT4 RECEPTOR AGONISTS | THERAVANCE INC (US) | 2009-11-11 | — | — | EP | disclosed |