Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 18/20 | 0.55 |
| ▸ | RXRB | P28702 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13318230 | 1.00 | FFAR1 (0.55) | FFAR1RXRBMAPT | |
| SCHEMBL13318227 | 0.91 | FFAR1 (0.63) | FFAR1RXRB | |
| SCHEMBL13616771 | 0.91 | FFAR1 (0.63) | FFAR1RXRB | |
| SCHEMBL3550749 | 0.90 | FFAR1 (0.64) | FFAR1RXRB | |
| SCHEMBL3550750 | 0.90 | FFAR1 (0.64) | FFAR1RXRB | |
| SCHEMBL13616792 | 0.88 | FFAR1 (0.51) | FFAR1MAPT | |
| SCHEMBL13318245 | 0.88 | FFAR1 (0.51) | FFAR1MAPT | |
| SCHEMBL14191137 | 0.85 | FFAR1 (0.56) | FFAR1MAPT | |
| SCHEMBL13318400 | 0.85 | FFAR1 (0.54) | FFAR1MAPT | |
| SCHEMBL13318404 | 0.82 | FFAR1 (0.53) | FFAR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275598-A1 | Conformationally constrained 3-(4-hydroxy-phenyl)-substituted-propanoic acids useful for treating metabolic disorders | AMGEN INC. (US) | 2009-11-05 | — | — | US | disclosed |
| US-20090275598-A1 | Conformationally constrained 3-(4-hydroxy-phenyl)-substituted-propanoic acids useful for treating metabolic disorders | AMGEN INC. (US) | 2009-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090275598-A1 | Conformationally constrained 3-(4-hydroxy-phenyl)-substituted-propanoic acids useful for treating metabolic disorders | PC, PNLIP, PDHX | FFAR1 51/4885RXRB 447/4885MAPT 4094/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.