Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3044855 | 0.81 | PTGDR2 (0.79) | PTGDR2PKMTDP1KDM4ETSHR | |
| SCHEMBL8528987 | 0.81 | PTGDR2 (0.55) | PTGDR2PKMTDP1MAPTTSHR | |
| SCHEMBL4138843 | 0.79 | PKM (0.71) | PTGDR2PKMTDP1KDM4EHTT | |
| SCHEMBL14066214 | 0.79 | PTGDR2 (0.60) | PTGDR2PKMTDP1KDM4ETSHR | |
| SCHEMBL3046012 | 0.79 | PTGDR2 (0.54) | PTGDR2PKMTDP1MAPTKDM4E | |
| SCHEMBL4143335 | 0.79 | TDP1 (0.70) | PTGDR2TDP1MAPTKDM4ETSHR | |
| SCHEMBL4147094 | 0.77 | KDM4E (0.59) | PTGDR2MAPTKDM4EHTTPOLB | |
| SCHEMBL7566116 | 0.77 | PTGDR2 (0.63) | PTGDR2PKM | |
| SCHEMBL16168181 | 0.77 | ALDH1A1 (0.53) | TDP1MAPTKDM4EHTTPOLB | |
| SCHEMBL14076372 | 0.76 | CYP2C19 (0.68) | PTGDR2PKMTDP1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2113258-A1 | AURONE DERIVATIVE-CONTAINING COMPOSITION FOR DIAGNOSIS | Nagasaki University (JP) | 2009-11-04 | — | — | EP | disclosed |