Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 3/20 | 0.35 |
| ▸ | FDPS | P14324 | 6/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | SCN1A | P35498 | 1/20 | 0.31 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.31 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.30 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2561263 | 0.87 | PIK3CD (0.45) | GGPS1PIK3CD | |
| SCHEMBL9387067 | 0.82 | PIK3CD (0.44) | FDPSPIK3CDSCN1ASCN2ASCN3A | |
| SCHEMBL29955365 | 0.81 | PIK3CD (0.34) | PIK3CD | |
| SCHEMBL29169584 | 0.79 | ALDH1A1 (0.42) | TSHRHIF1A | |
| SCHEMBL25075478 | 0.77 | CHRM2 (0.42) | GGPS1FDPSPIK3CDSCN1ASCN2A | |
| SCHEMBL9025471 | 0.77 | PIK3CD (0.52) | FDPSPIK3CDSCN1ASCN2ASCN3A | |
| SCHEMBL8853018 | 0.77 | CA12 (0.42) | TSHRHIF1A | |
| SCHEMBL29956245 | 0.76 | TSHR (0.52) | GGPS1FDPSTSHRAGTR1OPRM1 | |
| SCHEMBL26968850 | 0.76 | PIK3CD (0.37) | FDPSPIK3CDSCN1ASCN2ASCN3A | |
| SCHEMBL18596478 | 0.75 | LMNA (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| EP-1742908-B1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2009-11-11 | — | — | EP | disclosed |