Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB3 | P13945 | 1/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 2/20 | 0.31 |
| ▸ | BTK | Q06187 | 1/20 | 0.31 |
| ▸ | ITK | Q08881 | 1/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.31 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.31 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13617061 | 0.93 | ADRB3 (0.44) | ADRB3ADRA2BADRA2CCYP3A4CTSB | |
| SCHEMBL8001496 | 0.91 | CTSB (0.47) | ADRB3ADRA2BADRA2CCYP3A4CTSB | |
| SCHEMBL7869280 | 0.88 | ADRB3 (0.49) | ADRB3ADRA2BADRA2CCYP3A4CTSB | |
| SCHEMBL13617069 | 0.86 | ADRB3 (0.48) | ADRB3ADRA2BADRA2CCYP3A4CTSB | |
| SCHEMBL13757826 | 0.86 | ADRB3 (0.54) | ADRB3ADRA2BADRA2CCYP3A4CTSB | |
| SCHEMBL7875375 | 0.83 | ADRB3 (0.46) | ADRB3ADRA2BADRA2CCYP3A4CTSB | |
| SCHEMBL7880803 | 0.82 | ADRB3 (0.52) | ADRB3ADRA2BADRA2CCYP3A4CTSB | |
| SCHEMBL7871842 | 0.82 | ADRB3 (0.44) | ADRB3ADRA2BADRA2CCYP3A4CTSB | |
| SCHEMBL2383782 | 0.82 | CTSB (0.44) | ADRB3ADRA2BADRA2CCYP3A4CTSB | |
| SCHEMBL2383787 | 0.82 | CTSB (0.44) | ADRB3ADRA2BADRA2CCYP3A4CTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090285773-A1 | Hepatitis C Virus Inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2009-11-19 | — | — | US | disclosed |
| US-20090285773-A1 | Hepatitis C Virus Inhibitors | BRISTOL-MYERS SQUIBB COMPANY | 2009-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090285773-A1 | Hepatitis C Virus Inhibitors | HAVCR2, HCCS, PYGL | ADRB3 3508/4885ADRA2B 3612/4885ADRA2C 3036/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.