Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CA12 | O43570 | 3/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | STAT3 | P40763 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.34 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.34 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.34 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2151200 | 0.82 | CA12 (0.49) | ALDH1A1CA12CA2CA9STAT3 | |
| SCHEMBL3117255 | 0.81 | CA12 (0.36) | KMT2AMEN1ALDH1A1TSHRCA12 | |
| SCHEMBL3116629 | 0.81 | CA12 (0.36) | KMT2AMEN1ALDH1A1TSHRCA12 | |
| SCHEMBL3833448 | 0.81 | CA12 (0.36) | KMT2AMEN1ALDH1A1TSHRCA12 | |
| SCHEMBL7213256 | 0.81 | CA12 (0.36) | KMT2AMEN1ALDH1A1TSHRCA12 | |
| SCHEMBL3483301 | 0.80 | PSMD10 (0.41) | KMT2AMEN1ALDH1A1CA12CA2 | |
| SCHEMBL4290352 | 0.79 | CA12 (0.47) | ALDH1A1CA12CA2CA9STAT3 | |
| SCHEMBL3122917 | 0.79 | PLA2G2C (0.34) | KMT2AMEN1ALDH1A1TSHRCA12 | |
| SCHEMBL18530452 | 0.78 | PSMD10 (0.40) | KMT2AMEN1ALDH1A1CA12CA2 | |
| SCHEMBL8724738 | 0.78 | STAT3 (0.36) | KMT2AMEN1ALDH1A1TSHRSTAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943240-B1 | CHEMICAL PROCESS | ASTRAZENECA AB (SE) | 2009-11-11 | — | — | EP | disclosed |