Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.36 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
| ▸ | RABGGTB | P53611 | 1/20 | 0.33 |
| ▸ | RABGGTA | Q92696 | 1/20 | 0.33 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.33 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12944323 | 0.81 | ALDH1A1 (0.43) | STAT3KMT2AALDH1A1MEN1TSHR | |
| SCHEMBL5413300 | 0.80 | SERPINE1 (0.40) | STAT3KMT2AALDH1A1MEN1TSHR | |
| SCHEMBL7366081 | 0.79 | STAT3 (0.42) | STAT3NR1D1KMT2AALDH1A1MEN1 | |
| SCHEMBL2058187 | 0.79 | GAA (0.42) | STAT3KMT2AALDH1A1 | |
| SCHEMBL14788867 | 0.79 | NR1D1 (0.34) | NR1D1KMT2AALDH1A1MEN1CYP24A1 | |
| SCHEMBL15887428 | 0.79 | NR1D1 (0.34) | NR1D1KMT2AALDH1A1MEN1CYP24A1 | |
| SCHEMBL14777287 | 0.79 | NR1D1 (0.34) | NR1D1KMT2AALDH1A1MEN1CYP24A1 | |
| SCHEMBL11153442 | 0.78 | ALDH1A1 (0.36) | STAT3KMT2AALDH1A1MEN1CYP24A1 | |
| SCHEMBL13617344 | 0.78 | KMT2A (0.37) | STAT3NR1D1KMT2AALDH1A1MEN1 | |
| SCHEMBL15107672 | 0.78 | ABCG2 (0.33) | STAT3NR1D1KMT2AALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5854410-A | Oligonucleoside cleavage compounds and therapies | GENTA INCORPORATED (US) | 1998-12-29 | — | — | US | disclosed |
| WO-1995026733-A1 | OLIGONUCLEOSIDE CLEAVAGE COMPOUNDS AND THERAPIES | GENTA INCORPORATED (US) | 1995-10-12 | — | — | WO | disclosed |