Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.35 |
| ▸ | MPL | P40238 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.33 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9962916 | 0.97 | PTPN11 (0.35) | PTPN11MPLCYP1A2KDM4EMEN1 | |
| SCHEMBL6126028 | 0.94 | MPL (0.37) | PTPN11MPLCYP1A2KDM4EMEN1 | |
| SCHEMBL10030207 | 0.82 | AURKA (0.35) | PTPN11CYP1A2KDM4EMEN1ALDH1A1 | |
| SCHEMBL12213942 | 0.82 | PTPN11 (0.34) | PTPN11KDM4EMEN1ALDH1A1TP53 | |
| SCHEMBL13376063 | 0.82 | AURKA (0.35) | PTPN11CYP1A2KDM4EMEN1ALDH1A1 | |
| SCHEMBL12213939 | 0.79 | FABP3 (0.31) | PTPN11 | |
| SCHEMBL4957991 | 0.78 | MPL (0.49) | PTPN11MPLCYP1A2KDM4EMEN1 | |
| SCHEMBL29440243 | 0.78 | MPL (0.49) | PTPN11MPLCYP1A2KDM4EMEN1 | |
| SCHEMBL112192 | 0.78 | MPL (0.49) | PTPN11MPLCYP1A2KDM4EMEN1 | |
| SCHEMBL29431679 | 0.78 | MPL (0.49) | PTPN11MPLCYP1A2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090280147-A1 | Compositions comprising dye-loaded particles | NOXELL CORPORATION | 2009-11-12 | — | — | US | disclosed |
| US-20090263658-A1 | Dye-loaded particles | THE PROCTER & GAMBLE COMPANY | 2009-10-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090280147-A1 | Compositions comprising dye-loaded particles | CD68, ASAH2, SORT1 | PTPN11 3238/4885MPL 4642/4885CYP1A2 999/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.