SCHEMBL13617400

SCHEMBL13617400

CC(C)(C)c1cc(-c2cc(C(C)(C)C)cc(C(C)(C)C)c2Op2oc3ccccc3c3ccccc3o2)c(OPOc2ccccc2-c2ccccc2O)c(C(C)(C)C)c1

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
RXRA P19793 4/20 0.31
RXRB P28702 4/20 0.31
RXRG P48443 4/20 0.31
RARA P10276 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29879856 0.83 RXRA (0.33) RXRARXRBRXRGRARA
SCHEMBL130725 0.83 RXRA (0.33) RXRARXRBRXRGRARA
SCHEMBL17285537 0.79 TNFRSF1A (0.33) RXRARXRBRXRGRARA
SCHEMBL19248350 0.78 APEX1 (0.35)
SCHEMBL15685032 0.76
SCHEMBL14544160 0.75 ALDH1A1 (0.32)
SCHEMBL22044280 0.75
SCHEMBL17280445 0.75 RXRA (0.32) RXRARXRBRXRGRARA
SCHEMBL13431490 0.74 NPC1 (0.32) RXRARXRBRXRGRARA
SCHEMBL13627006 0.73 ALDH1A1 (0.37) RXRARXRBRXRGRARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1745021-B1 HYDROFORMYLATION PROCESS FOR PHARMACEUTICAL INTERMEDIATE REDDY S LAB EU LTD DR (GB) 2009-11-11 EP disclosed