Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 6/20 | 0.48 |
| ▸ | CPB1 | P15086 | 3/20 | 0.48 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.48 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 1/20 | 0.43 |
| ▸ | SIRT2 | Q8IXJ6 | 7/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3838443 | 0.91 | CPB2 (0.53) | CPB2CPB1CTSSCTSLCTSB | |
| SCHEMBL18292156 | 0.90 | CPB2 (0.42) | CPB2CPB1KLK5 | |
| SCHEMBL19508750 | 0.83 | KLK5 (0.51) | KLK5CTSSCTSLCTSBCTSK | |
| SCHEMBL11913040 | 0.83 | SIRT2 (0.61) | KLK5CTSSCTSLCTSBCTSK | |
| SCHEMBL13810396 | 0.83 | SIRT2 (0.61) | KLK5CTSSCTSLCTSBCTSK | |
| SCHEMBL8345705 | 0.82 | KLK5 (0.49) | CPB2CPB1KLK5CTSSCTSL | |
| SCHEMBL3439706 | 0.80 | KLK5 (0.41) | CPB2KLK5CTSSCTSLCTSB | |
| SCHEMBL9838791 | 0.80 | KLK5 (0.41) | CPB2KLK5CTSSCTSLCTSB | |
| SCHEMBL16464699 | 0.78 | HDAC6 (0.60) | KLK5CTSSCTSLCTSBCTSK | |
| SCHEMBL16464697 | 0.78 | HDAC6 (0.60) | KLK5CTSSCTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1311488-B1 | SUBSTITUTED IMIDAZOLES AS TAFIA INHIBITORS | PFIZER LTD (GB) | 2009-11-04 | — | — | EP | disclosed |