Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1B | P49286 | 6/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | EGFR | P00533 | 2/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.46 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17364441 | 0.90 | MEN1 (0.55) | MTNR1BMTNR1AMEN1KMT2AMAPT | |
| SCHEMBL13302353 | 0.79 | MEN1 (0.69) | MTNR1BMTNR1AMEN1KMT2AMAPT | |
| SCHEMBL1921496 | 0.78 | MTNR1B (0.72) | MTNR1BMTNR1AMEN1KMT2AMAPT | |
| SCHEMBL1085867 | 0.78 | MEN1 (0.71) | MTNR1BMTNR1AMEN1KMT2AMAPT | |
| SCHEMBL13550016 | 0.76 | MTNR1B (0.51) | MTNR1BMTNR1AMEN1KMT2AMAPT | |
| SCHEMBL2112594 | 0.74 | KMT2A (0.71) | MTNR1BMTNR1AMEN1KMT2AMAPT | |
| SCHEMBL30741237 | 0.74 | KMT2A (0.71) | MTNR1BMTNR1AMEN1KMT2AMAPT | |
| SCHEMBL30741242 | 0.74 | KMT2A (0.71) | MTNR1BMTNR1AMEN1KMT2AMAPT | |
| SCHEMBL9479511 | 0.74 | MTNR1B (0.68) | MTNR1BMTNR1AMEN1KMT2AMAPT | |
| SCHEMBL9479608 | 0.74 | MTNR1B (0.68) | MTNR1BMTNR1AMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090275070-A1 | Compounds and Methods of Identifying, Synthesizing, Optimizing and Profiling Protein Modulators | HOUSEY GERARD M | 2009-11-05 | — | — | US | disclosed |