Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | NPC1 | O15118 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.52 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.52 |
| ▸ | FYN | P06241 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 4/20 | 0.50 |
| ▸ | SYK | P43405 | 1/20 | 0.50 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.49 |
| ▸ | ERBB3 | P21860 | 1/20 | 0.49 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.48 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13617494 | 0.90 | MTNR1B (0.52) | MEN1KMT2AMAPTMAPK1NPC1 | |
| SCHEMBL13302353 | 0.83 | MEN1 (0.69) | MEN1KMT2AMAPTMAPK1NPC1 | |
| SCHEMBL14127702 | 0.83 | KMT2A (0.55) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL29636514 | 0.83 | KMT2A (0.55) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL14127743 | 0.82 | MAPT (0.63) | MEN1KMT2AMAPTMAPK1NPC1 | |
| SCHEMBL29636429 | 0.82 | MAPT (0.63) | MEN1KMT2AMAPTMAPK1NPC1 | |
| SCHEMBL29636445 | 0.82 | KMT2A (0.54) | MEN1KMT2AMAPTMAPK1NPC1 | |
| SCHEMBL14127745 | 0.82 | KMT2A (0.54) | MEN1KMT2AMAPTMAPK1NPC1 | |
| SCHEMBL1921496 | 0.81 | MTNR1B (0.72) | MEN1KMT2AMAPTMAPK1NPC1 | |
| SCHEMBL1085867 | 0.81 | MEN1 (0.71) | MEN1KMT2AMAPTMAPK1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11714080-B2 | Compounds and methods of identifying, synthesizing, optimizing and profiling protein modulators | HMI Medical Innovations, LLC (US) | 2023-08-01 | — | — | US | disclosed |
| US-11692998-B2 | Compounds and methods of identifying, synthesizing, optimizing and profiling protein modulators | HMI Medical Innovations, LLC (US) | 2023-07-04 | — | — | US | disclosed |
| US-10018619-B2 | Compounds and method of identifying, synthesizing, optimizing and profiling protein modulators | HMI Medical Innovations, LLC (US) | 2018-07-10 | — | — | US | disclosed |
| US-20170191986-A1 | Compounds and Method of Identifying, Synthesizing, Optimizing and Profiling Protein Modulators | HMI Medical Innovations, LLC | 2017-07-06 | — | — | US | disclosed |
| US-9645137-B2 | Compounds and method of identifying, synthesizing, optimizing and profiling protein modulators | HMI Medical Innovations, LLC (US) | 2017-05-09 | — | — | US | disclosed |
| US-20160153965-A1 | Compounds and Method of Identifying, Synthesizing, Optimizing and Profiling Protein Modulators | HMI Medical Innovations, LLC | 2016-06-02 | — | — | US | disclosed |
| US-9222933-B2 | Compounds and method of identifying, synthesizing, optimizing and profiling protein modulators | HMI Medical Innovations, LLC (US) | 2015-12-29 | — | — | US | disclosed |